Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17637043 | 1.00 | HTT (0.58) | HTTL3MBTL1TSHRNPSR1MEN1 | |
| SCHEMBL15356260 | 0.88 | MEN1 (0.45) | HTTL3MBTL1TSHRNPSR1MEN1 | |
| SCHEMBL4753042 | 0.88 | MEN1 (0.45) | HTTL3MBTL1TSHRNPSR1MEN1 | |
| SCHEMBL13146717 | 0.85 | MEN1 (0.42) | HTTL3MBTL1TSHRNPSR1MEN1 | |
| SCHEMBL4753133 | 0.85 | MEN1 (0.42) | HTTL3MBTL1TSHRNPSR1MEN1 | |
| SCHEMBL19728213 | 0.81 | MEN1 (0.40) | HTTL3MBTL1TSHRNPSR1MEN1 | |
| SCHEMBL18927063 | 0.81 | MEN1 (0.43) | HTTL3MBTL1TSHRNPSR1MEN1 | |
| SCHEMBL17083647 | 0.80 | ALDH1A1 (0.45) | HTTTSHRMEN1KMT2AMAPT | |
| SCHEMBL12957809 | 0.80 | ALDH1A1 (0.45) | HTTTSHRMEN1KMT2AMAPT | |
| SCHEMBL50372 | 0.80 | ALDH1A1 (0.45) | HTTTSHRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040896-B2 | Silane functionalized compounds and compositions thereof | Hexion, Inc. (US) | 2018-08-07 | — | — | US | disclosed |
| US-20160090439-A1 | SILANE FUNCTIONALIZED COMPOUNDS AND COMPOSITIONS THEREOF | MOMENTIVE PERFORMANCE MATERIALS INC. | 2016-03-31 | — | — | US | disclosed |
| US-20160090439-A1 | SILANE FUNCTIONALIZED COMPOUNDS AND COMPOSITIONS THEREOF | MOMENTIVE PERFORMANCE MATERIALS INC. | 2016-03-31 | — | — | US | disclosed |
| WO-2016049192-A1 | SILANE FUNCTIONALIZED COMPOUNDS AND COMPOSITIONS THEREOF | HEXION INC. (US) | 2016-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160090439-A1 | SILANE FUNCTIONALIZED COMPOUNDS AND COMPOSITIONS THEREOF | ILK, CAD, CAPG | HTT 3115/4885L3MBTL1 3165/4885TSHR 4832/4885 |
| US-10040896-B2 | Silane functionalized compounds and compositions thereof | ILK, CAD, CAPG | HTT 3115/4885L3MBTL1 3165/4885TSHR 4832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.