Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19546794 | 0.84 | GPR3 (0.34) | GPR3MAPT | |
| SCHEMBL27860147 | 0.79 | GPR3 (0.33) | GPR3MEN1POLBMAPTDUSP3 | |
| SCHEMBL29520293 | 0.79 | GPR3 (0.39) | GPR3MEN1POLBMAPTDUSP3 | |
| SCHEMBL14951403 | 0.79 | GPR3 (0.39) | GPR3MEN1POLBMAPTDUSP3 | |
| SCHEMBL20663069 | 0.76 | MAPT (0.36) | GPR3MAPT | |
| SCHEMBL21942540 | 0.76 | GPR3 (0.38) | GPR3POLBMAPTDUSP3TDP1 | |
| SCHEMBL19544229 | 0.76 | ALDH1A1 (0.40) | GPR3POLBMAPTTDP1 | |
| SCHEMBL21941579 | 0.73 | LPL (0.33) | — | |
| SCHEMBL24614226 | 0.70 | IDO1 (0.41) | — | |
| SCHEMBL19546409 | 0.69 | CYP1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016045769-A1 | HETEROCYCLIC COMPOUNDS WITH BENZO[C]COUMARIN-STRUCTURES | MERCK PATENT GMBH (DE) | 2016-03-31 | — | — | WO | disclosed |