SCHEMBL27860147

SCHEMBL27860147

CC1(C)COB(c2cccc3sc4ccccc4c23)OC1(C)C

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.33
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
DUSP3 P51452 1/20 0.32
BLM P54132 1/20 0.32
PTPN5 P54829 1/20 0.32
KMT2A Q03164 1/20 0.32
PTPN11 Q06124 1/20 0.32
MCL1 Q07820 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29520293 0.85 GPR3 (0.39) GPR3MEN1POLBMAPTDUSP3
SCHEMBL14951403 0.85 GPR3 (0.39) GPR3MEN1POLBMAPTDUSP3
SCHEMBL17638034 0.79 GPR3 (0.34) GPR3MEN1POLBMAPTDUSP3
SCHEMBL22135458 0.73 BRDT (0.35) GPR3MEN1POLBMAPTDUSP3
SCHEMBL27335211 0.72 BRDT (0.36) GPR3MEN1POLBMAPTDUSP3
SCHEMBL27989326 0.72 ALDH1A1 (0.37) MAPTTDP1
SCHEMBL22303410 0.72 MAPT (0.36) GPR3MEN1POLBMAPTDUSP3
SCHEMBL27960198 0.72 LPL (0.34)
SCHEMBL19916973 0.71 LPL (0.40)
SCHEMBL19916999 0.71 NQO1 (0.39) GPR3MEN1POLBMAPTDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102477142-A Conjugated block polymer, and its preparation method and application ZHISHAN BO 2012-05-30 CN claimed
CN-102477142-A Conjugated block polymer, and its preparation method and application ZHISHAN BO 2012-05-30 CN disclosed