Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 8/20 | 0.48 |
| ▸ | ANPEP | P15144 | 2/20 | 0.48 |
| ▸ | ECE1 | P42892 | 7/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501480 | 0.92 | MME (0.52) | ACE2MMEANPEPECE1 | |
| SCHEMBL26122670 | 0.81 | ACE2 (0.50) | ACE2MMEANPEPECE1 | |
| SCHEMBL23515632 | 0.80 | MME (0.51) | ACE2MMEANPEPECE1 | |
| SCHEMBL3701204 | 0.77 | CPA1 (0.57) | MME | |
| SCHEMBL6923615 | 0.77 | ACE2 (0.58) | ACE2MMEECE1 | |
| SCHEMBL7613489 | 0.76 | ACE2 (0.69) | ACE2MMEECE1 | |
| SCHEMBL7613146 | 0.76 | ACE2 (0.69) | ACE2MMEECE1 | |
| SCHEMBL24991304 | 0.76 | ACE2 (0.69) | ACE2MMEECE1 | |
| SCHEMBL1764208 | 0.76 | ACE2 (0.69) | ACE2MMEECE1 | |
| SCHEMBL20575445 | 0.76 | MME (0.77) | MMEANPEPECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787171-B | Industrial preparation method of compound | 智腾大中华区有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-114787171-A | Industrial process for the preparation of the disodium salt of ((2S) -3- ([1, 1' -biphenyl ] -4-yl) -2- ((hydroxy ((1R) -1- (((1- (isobutyroyloxy) ethoxy) carbonyl) amino) ethyl) phosphoryl) methyl) propionyl) -L-alanine | 领先药物公司 | 2022-07-22 | — | — | CN | disclosed |
| US-10131681-B2 | Aminophosphinic derivatives that can be used in the treatment of pain | PHARMALEADS (FR) | 2018-11-20 | — | — | US | disclosed |
| US-20140161839-A1 | AMINOPHOSPHINIC DERIVATIVES THAT CAN BE USED IN THE TREATMENT OF PAIN | PHARMALEADS (FR) | 2014-06-12 | — | — | US | disclosed |
| US-8703747-B2 | Aminophosphinic derivatives that can be used in the treatment of pain | PHARMALEADS (FR) | 2014-04-22 | — | — | US | disclosed |
| US-20110124601-A1 | AMINOPHOSPHINIC DERIVATIVES THAT CAN BE USED IN THE TREATMENT OF PAIN | PHARMALEADS | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124601-A1 | AMINOPHOSPHINIC DERIVATIVES THAT CAN BE USED IN THE TREATMENT OF PAIN | OPRM1, HRH3, HRH4 | ACE2 3562/4885MME 3670/4885ANPEP 2038/4885 |
| US-10131681-B2 | Aminophosphinic derivatives that can be used in the treatment of pain | OPRM1, HRH3, HRH4 | ACE2 3454/4885MME 3490/4885ANPEP 2062/4885 |
| US-20140161839-A1 | AMINOPHOSPHINIC DERIVATIVES THAT CAN BE USED IN THE TREATMENT OF PAIN | OPRM1, HRH3, HRH4 | ACE2 3454/4885MME 3490/4885ANPEP 2062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.