Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.51 |
| ▸ | ANPEP | P15144 | 2/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23515629 | 0.92 | ACE2 (0.45) | MMEANPEPACE2ECE1 | |
| SCHEMBL26122670 | 0.84 | ACE2 (0.50) | MMEANPEPACE2ECE1 | |
| SCHEMBL23501480 | 0.81 | MME (0.52) | MMEANPEPACE2ECE1 | |
| SCHEMBL6923615 | 0.80 | ACE2 (0.58) | MMEACE2ECE1 | |
| SCHEMBL24991304 | 0.80 | ACE2 (0.69) | MMEACE2ECE1 | |
| SCHEMBL7613146 | 0.80 | ACE2 (0.69) | MMEACE2ECE1 | |
| SCHEMBL7613489 | 0.80 | ACE2 (0.69) | MMEACE2ECE1 | |
| SCHEMBL1764208 | 0.80 | ACE2 (0.69) | MMEACE2ECE1 | |
| SCHEMBL1764061 | 0.80 | ACE2 (0.49) | MMEANPEPACE2ECE1 | |
| SCHEMBL24991024 | 0.78 | PTPN1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4073080-B1 | PROCESS FOR INDUSTRIAL PREPARATION OF THE DISODIUM SALT OF ((2S)-3-([1,1'-BIPHENYL]-4-YL)-2-((HYDROXY((1R)-1-(((1-(ISOBUTYRYLOXY)ETHOXY)CARBONYL)AMINO)ETHYL)PHOSPHORYL)METHYL)PROPANOYL)-L-ALANINE | KOS THERAPEUTICS INC (US) | 2023-10-11 | — | — | EP | disclosed |
| US-20230041504-A1 | METHOD FOR THE INDUSTRIAL PREPARATION OF THE DISODIUM SALT OF ((2S)-3-([1,1'-BIPHENYL]-4-YL)-2-((HYDROXY((1R)-1-(((1-(ISOBUTYRYLOXY)ETHOXY)CARBONYL)AMINO)ETHYL)PHOSPHORYL) METHYL)PROPANOYL)-L-ALANINE | KOS THERAPEUTICS, INC. | 2023-02-09 | — | — | US | disclosed |
| WO-2021116617-A1 | PROCESS FOR INDUSTRIAL PREPARATION OF THE DISODIUM SALT OF ((2S)-3-([1,1'-BIPHENYL]-4-YL)-2-((HYDROXY((1R)-1-(((1-(ISOBUTYRYLOXY)ETHOXY)CARBONYL)AMINO)ETHYL)PHOSPHORYL)METHYL)PROPANOYL)-L-ALANINE | PHARMALEADS (FR) | 2021-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230041504-A1 | METHOD FOR THE INDUSTRIAL PREPARATION OF THE DISODIUM SALT OF ((2S)-3-([1,1'-BIPHENYL]-4-YL)-2-((HYDROXY((1R)-1-(((1-(ISOBUTYRYLOXY)ETHOXY)CARBONYL)AMINO)ETHYL)PHOSPHORYL) METHYL)PROPANOYL)-L-ALANINE | CHAMP1, AADAT, PTMS | MME 1021/4885ANPEP 191/4885ACE2 972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.