Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17633968 | 0.91 | LRRK2 (0.35) | PDE2ALRRK2EGLN1RORCSSTR4 | |
| SCHEMBL17640473 | 0.90 | LRRK2 (0.34) | PDE2ALRRK2EGLN1RORC | |
| SCHEMBL17640665 | 0.90 | PDE2A (0.35) | PDE2ALRRK2RORC | |
| SCHEMBL17640666 | 0.87 | CYP1A2 (0.33) | LRRK2 | |
| SCHEMBL17609374 | 0.85 | POLB (0.40) | PDE2APOLBLRRK2DRD2DRD4 | |
| SCHEMBL15933422 | 0.85 | POLB (0.37) | POLBLRRK2CRHR1EGLN1DDR1 | |
| SCHEMBL30711169 | 0.84 | POLB (0.43) | PDE2APOLBLRRK2DRD2DRD4 | |
| SCHEMBL17844030 | 0.84 | POLB (0.43) | PDE2APOLBLRRK2DRD2DRD4 | |
| SCHEMBL17640652 | 0.83 | PDE2A (0.33) | PDE2ALRRK2 | |
| SCHEMBL15929740 | 0.83 | POLB (0.36) | PDE2APOLBLRRK2CRHR1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016046071-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-31 | — | — | WO | disclosed |