Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CASP1 | P29466 | 4/20 | 0.33 |
| ▸ | CASP7 | P55210 | 4/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17640665 | 0.89 | PDE2A (0.35) | LRRK2LMNA | |
| SCHEMBL17633968 | 0.87 | LRRK2 (0.35) | LRRK2HSD17B10 | |
| SCHEMBL17640658 | 0.87 | PDE2A (0.36) | LRRK2 | |
| SCHEMBL17640473 | 0.86 | LRRK2 (0.34) | LRRK2 | |
| SCHEMBL20182758 | 0.81 | POLB (0.44) | CYP1A2ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL17696194 | 0.81 | CYP1A2 (0.34) | CYP1A2ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL17640652 | 0.80 | PDE2A (0.33) | LRRK2 | |
| SCHEMBL18926498 | 0.76 | GRIN2B (0.34) | CYP1A2ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL25885629 | 0.75 | POLB (0.39) | GRIN2BGRIN1 | |
| SCHEMBL30989728 | 0.75 | POLB (0.39) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016046071-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-31 | — | — | WO | disclosed |