Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17640658 | 0.90 | PDE2A (0.36) | PDE2ARORCLRRK2 | |
| SCHEMBL17640666 | 0.89 | CYP1A2 (0.33) | LMNALRRK2 | |
| SCHEMBL17633968 | 0.86 | LRRK2 (0.35) | PDE2ARORCLRRK2 | |
| SCHEMBL17640473 | 0.85 | LRRK2 (0.34) | PDE2ARORCLRRK2 | |
| SCHEMBL20182759 | 0.83 | POLB (0.43) | RORCKCNH2 | |
| SCHEMBL30989728 | 0.83 | POLB (0.39) | MCHR1DGAT1CHRNB1CHRNB2CHRNB4 | |
| SCHEMBL25885629 | 0.83 | POLB (0.39) | MCHR1DGAT1CHRNB1CHRNB2CHRNB4 | |
| SCHEMBL17696196 | 0.81 | PTGS2 (0.36) | LMNARORCNR1H2KCNH2 | |
| SCHEMBL17640652 | 0.81 | PDE2A (0.33) | PDE2ALRRK2 | |
| SCHEMBL30989724 | 0.80 | POLB (0.33) | RORCDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016046071-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-31 | — | — | WO | disclosed |