Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 3/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17640658 | 0.91 | PDE2A (0.36) | LRRK2SSTR4EGLN1PDE2ARORC | |
| SCHEMBL17640473 | 0.90 | LRRK2 (0.34) | LRRK2EGLN1PDE2ARORC | |
| SCHEMBL17640666 | 0.87 | CYP1A2 (0.33) | LRRK2HSD17B10 | |
| SCHEMBL17640665 | 0.86 | PDE2A (0.35) | LRRK2PDE2ARORC | |
| SCHEMBL17640652 | 0.83 | PDE2A (0.33) | LRRK2PDE2A | |
| SCHEMBL17633956 | 0.82 | LRRK2 (0.33) | LRRK2SSTR4EGLN1 | |
| SCHEMBL21641644 | 0.81 | POLB (0.45) | LRRK2KDM4EHSD17B10 | |
| SCHEMBL17688763 | 0.80 | PTGS2 (0.32) | LRRK2KDM4EHSD17B10 | |
| SCHEMBL17609378 | 0.79 | POLB (0.42) | LRRK2HSD17B10 | |
| SCHEMBL31194358 | 0.79 | POLB (0.38) | LRRK2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016046071-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-31 | — | — | WO | disclosed |
| WO-2016046071-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-31 | — | — | WO | disclosed |