Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176418 | 0.93 | EGLN1 (0.36) | LMNA | |
| SCHEMBL6267404 | 0.92 | ALDH1A1 (0.40) | LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL8839158 | 0.89 | LMNA (0.44) | LMNATSHRMAPTMAPK1ALDH1A1 | |
| SCHEMBL9323704 | 0.88 | MGAM (0.38) | — | |
| SCHEMBL8839122 | 0.88 | MEN1 (0.33) | — | |
| SCHEMBL8839181 | 0.86 | LMNA (0.54) | LMNATSHRMAPTMAPK1ALDH1A1 | |
| SCHEMBL8839276 | 0.86 | LMNA (0.54) | LMNATSHRMAPTMAPK1ALDH1A1 | |
| SCHEMBL8839107 | 0.86 | LMNA (0.54) | LMNATSHRMAPTMAPK1ALDH1A1 | |
| SCHEMBL1070487 | 0.83 | MGAM (0.39) | — | |
| SCHEMBL9323718 | 0.83 | MGAM (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8551332-B2 | Affinity particle and affinity separation method | SHISEIDO COMPANY, LTD. (JP) | 2013-10-08 | — | — | US | disclosed |
| EP-1759761-B1 | AFFINITY PARTICLE AND AFFINITY SEPARATION METHOD | SHISEIDO CO LTD (JP) | 2011-07-27 | — | — | EP | disclosed |
| EP-1750127-B1 | Method of affinity separation. | SHISEIDO CO LTD (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-20100137133-A1 | Affinity Particle And Affinity Separation Method | SHISEIDO COMPANY, LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| US-20090321357-A1 | Affinity Particle And Affinity Separation Method | SHISEIDO COMPANY, LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20090321358-A1 | Affinity Particle And Method Of Affinity Separation | SHISEIDO COMPANY, LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20070241054-A1 | Affinity Particle And Method Of Affinity Separation | SHISEIDO COMPANY, LTD. (JP) | 2007-10-18 | — | — | US | disclosed |
| US-20070181503-A1 | Affinity particle and affinity separation method | SHISEIDO COMPANY, LTD. (JP) | 2007-08-09 | — | — | US | disclosed |
| EP-1759761-A1 | AFFINITY PARTICLE AND AFFINITY SEPARATION METHOD | SHISEIDO COMPANY, LTD. (JP) | 2007-03-07 | — | — | EP | disclosed |
| EP-1750127-A1 | AFFINITY PARTICLE AND METHOD OF AFFINITY SEPARATION | Shiseido Company, Limited (JP) | 2007-02-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090321357-A1 | Affinity Particle And Affinity Separation Method | FCGR1A, ACP1, FCGR3B | LMNA 3292/4885TSHR 1965/4885POLB 3060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.