SCHEMBL1764557

SCHEMBL1764557

Cc1cn([C@H]2C[C@H](O)[C@@H](CO[P](=O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.65
POLB P06746 1/20 0.64
TYMS P04818 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28399790 0.92 POLB (0.66) TK1POLBTYMS
SCHEMBL19101649 0.92 POLB (0.66) TK1POLBTYMS
SCHEMBL17514032 0.92 POLB (0.66) TK1POLBTYMS
SCHEMBL210837 0.90 POLB (0.63) TK1POLB
SCHEMBL8349986 0.88 POLB (0.63) TK1POLBTYMS
SCHEMBL12918450 0.87 TK1 (0.69) TK1POLBTYMS
SCHEMBL17232081 0.87 TK1 (0.69) TK1POLBTYMS
SCHEMBL4804983 0.87 POLB (0.68) TK1POLBTYMS
SCHEMBL135209 0.87 TK1 (0.69) TK1POLBTYMS
SCHEMBL22943603 0.87 TK1 (0.69) TK1POLBTYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137638-B Bridged nucleic acid GuNA, method for producing same, and intermediate compound 田边三菱制药株式会社 2022-05-03 CN claimed
CN-107074911-B Peptide nucleic acid monomers and oligomers 优基艾森斯股份公司 2020-11-03 CN claimed
CN-110741053-A Coating composition 株式会社ADEKA 2020-01-31 CN claimed
CN-104136451-A Synthesis and use of nucleic acid compounds with conformationally constrained monomers MARINA BIOTECH INC 2014-11-05 CN claimed
CN-100351233-C Fullerene derivatives of the E-isomer LONGYONG JIANG (CN) 2007-11-28 CN claimed
CN-1190444-C Biosynthesis gene cluster of Nanchang UNIV SHANGHAI JIAOTONG (CN) 2005-02-23 CN claimed
CN-1317484-A Fullerene derivatives of the E-isomer JIANG LONGYONG (CN) 2001-10-17 CN claimed
US-5455233-A Detectors, antiinflammatory, antilipemic agents and antitumor agents UNIVERSITY OF NORTH CAROLINA (US) 1995-10-03 US claimed
WO-1994014981-A1 TREATMENT OF VIRAL INFECTIONS CHEN ROLLAND (US) 1994-07-07 WO claimed
CN-1034578-A The recombinant dna expression vector and the dna compound of isopenicillin N synthetic enzyme in the coding Aspergillus nidulans LILLY CO ELI (US) 1989-08-09 CN claimed
CN-88101644-A Recombinant DNA expression vectors and DNA compounds encoding desacetoxycephalosporane C synthase and desacetoxycephalosporane C synthase 1988-11-23 CN claimed
CN-114630911-B Enzymatic process for the preparation of UDP-GlcNAc 马克斯·普朗克科学促进学会 2024-06-28 CN disclosed
CN-113748212-B Enzymatic process for preparing GDP-fucose 马克斯·普朗克科学促进学会 2023-04-25 CN disclosed
CN-115968374-A Cross-linked nucleosides and nucleotides LIID制药股份有限公司 2023-04-14 CN disclosed
CN-109843302-B Compounds, compositions and methods for treating diseases F-星治疗公司 2022-11-29 CN disclosed
CN-1070409-A Prodrugs activated by targetted catalytic proteins IGEN INC (US) 1993-03-31 CN disclosed
WO-1991008213-A1 OLIGORIBONUCLOSIDE AND OLIGODEOXYRIBONUCLEOSIDE BORANOPHOSPHATES BORON BIOLOGICALS, INC. (US) 1991-06-13 WO disclosed
CN-1034578-A The recombinant dna expression vector and the dna compound of isopenicillin N synthetic enzyme in the coding Aspergillus nidulans LILLY CO ELI (US) 1989-08-09 CN disclosed
EP-0073826-A1 RAPID SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDES USING PHOSPHORUS OXYCHLORIDE ACTIVATION BIORESEARCH INC. (US) 1983-03-16 EP disclosed
WO-1982003079-A1 RAPID SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDES USING PHOSPHORUS OXYCHLORIDE ACTIVATION BIORESEARCH INC (US) 1982-09-16 WO disclosed