Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3201962 | 0.72 | — | — | |
| SCHEMBL5985571 | 0.71 | — | — | |
| SCHEMBL4492969 | 0.71 | — | — | |
| SCHEMBL19692379 | 0.71 | — | — | |
| SCHEMBL11894063 | 0.71 | — | — | |
| SCHEMBL8944768 | 0.71 | — | — | |
| SCHEMBL27952254 | 0.71 | NCF1 (0.39) | DYRK1AADORA2AADORA1 | |
| SCHEMBL4726446 | 0.71 | — | — | |
| SCHEMBL236001 | 0.71 | ALDH1A1 (0.33) | DYRK1AADORA2AADORA1 | |
| Cytosine SCHEMBL10496353 | 0.71 | DYRK1A (0.38) | DYRK1AADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374890-B1 | Fen-1 endonucleases, mixtures and cleavage methods | THIRD WAVE TECH INC (US) | 2012-11-14 | — | — | EP | disclosed |
| US-8288093-B2 | Forming a nucleic acid invasive cleavage structure on a target sequence and cleaving the nucleic acid invasive cleavage structure in a site-specific manner; fluorescence in-situ hybridization detection of cytomegalo virus | THIRD WAVE TECHNOLOGIES, INC. (US) | 2012-10-16 | — | — | US | disclosed |
| EP-2058407-B1 | Invasive cleavage of nucleic acids | THIRD WAVE TECH INC (US) | 2012-09-19 | — | — | EP | disclosed |
| EP-2354252-B1 | Invasive cleavage of nucleic acids | THIRD WAVE TECH INC (US) | 2012-08-29 | — | — | EP | disclosed |
| US-8182991-B1 | FEN-1 endonucleases, mixtures and cleavage methods | THIRD WAVE TECHNOLOGIES, INC. (US) | 2012-05-22 | — | — | US | disclosed |
| EP-1548130-B1 | Fen endonucleases | THIRD WAVE TECH INC (US) | 2012-01-18 | — | — | EP | disclosed |
| EP-2055781-B1 | FEN-1 endonucleases, mixtures and cleavage methods | THIRD WAVE TECH INC (US) | 2011-10-26 | — | — | EP | disclosed |
| EP-2374890-A2 | Fen-1 endonucleases, mixtures and cleavage methods | THIRD WAVE TECHNOLOGIES, INC. (US) | 2011-10-12 | — | — | EP | disclosed |
| EP-2354252-A1 | Invasive cleavage of nucleic acids | THIRD WAVE TECHNOLOGIES, INC. (US) | 2011-08-10 | — | — | EP | disclosed |
| US-7829314-B2 | Cleavage of nucleic acids | THIRD WAVE TECHNOLOGIES, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-6090543-A | DETECTING THE PRESENCE OF A TARGET NUCLEIC ACID MOLECULE BY MIXING TOGETHER CLEAVAGE MEANS, TARGET NUCLEIC ACID, AND COMPLEMENTARY OLIGONUCLEOTIDES; THEN DETECTING NON-TARGET CLEAVAGE PRODUCTS | THIRD WAVE TECHNOLOGIES, INC. (US) | 2000-07-18 | — | — | US | disclosed |
| EP-0994964-A1 | DETECTION OF NUCEIC ACIDS BY MULTIPLE SEQUENTIAL INVASIVE CLEAVAGES | THIRD WAVE TECHNOLOGIES, INC. (US) | 2000-04-26 | — | — | EP | disclosed |
| EP-0966542-A1 | FEN-1 ENDONUCLEASES, MIXTURES AND CLEAVAGE METHODS | THIRD WAVE TECHNOLOGIES, INC. (US) | 1999-12-29 | — | — | EP | disclosed |
| US-6001567-A | SCREENING FOR TARGET RNA MOLECULE; PROVIDING NUCLEASE, TARGET RNA, AND OLIGONUCLEOTIDES, MIXING, ALLOW ANNEALING, SCREEN FOR NON-TARGET CLEAVAGE PRODUCTS, ELECTROPHORETIC SEPARATION AND VISUALIZATION OF PRODUCTS | THIRD WAVE TECHNOLOGIES, INC. (US) | 1999-12-14 | — | — | US | disclosed |
| US-5994069-A | FORMING NUCLEIC ACID CLEAVAGE STRUCTURE ON TARGET SEQUENCE AND CLEAVING THE NUCLEIC ACID IN A SITE SPECIFIC MANNER USING STRUCTURE SPECIFIC 5'NUCLEASES THEN ANNEALING COMPLEMENTARY OLIGONUCLEOTIDES TO DETECT TARGET NUCLEIC ACID | THIRD WAVE TECHNOLOGIES, INC. (US) | 1999-11-30 | — | — | US | disclosed |
| US-5985557-A | TARGET NUCLEIC ACID AND OLIGONUCLEOTIDE MIXTURE | THIRD WAVE TECHNOLOGIES, INC. (US) | 1999-11-16 | — | — | US | disclosed |
| EP-0904286-A1 | INVASIVE CLEAVAGE OF NUCLEIC ACIDS | THIRD WAVE TECHNOLOGIES, INC. (US) | 1999-03-31 | — | — | EP | disclosed |
| WO-1998042873-A1 | DETECTION OF NUCEIC ACIDS BY MULTIPLE SEQUENTIAL INVASIVE CLEAVAGES | THIRD WAVE TECHNOLOGIES, INC. (US) | 1998-10-01 | — | — | WO | disclosed |
| WO-1998023774-A1 | FEN-1 ENDONUCLEASES, MIXTURES AND CLEAVAGE METHODS | THIRD WAVE TECHNOLOGIES, INC. (US) | 1998-06-04 | — | — | WO | disclosed |
| WO-1997027214-A1 | INVASIVE CLEAVAGE OF NUCLEIC ACIDS | THIRD WAVE TECHNOLOGIES, INC. (US) | 1997-07-31 | — | — | WO | disclosed |