Hydrochloric Acid

Hydrochloric Acid

SCHEMBL1765135

CCCCCCCCCC[P+](C)(C)Cc1ccccc1.[Cl-]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BDKRB2 known ✓ P30411 5/20 0.50
CSNK1E P49674 1/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
TP53 P04637 1/20 0.47
MAPK1 P28482 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HTT P42858 2/20 0.46
SIGMAR1 Q99720 2/20 0.46
DNM1 Q05193 2/20 0.44
EPHX2 P34913 1/20 0.43
PKM P14618 1/20 0.43
KCNH2 Q12809 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5091604 1.00 BDKRB2 (0.50) BDKRB2CSNK1EMEN1KMT2ATP53
Hydrochloric Acid SCHEMBL1249737 1.00 BDKRB2 (0.50) BDKRB2CSNK1EMEN1KMT2ATP53
Hydrochloric Acid SCHEMBL678168 1.00 BDKRB2 (0.50) BDKRB2CSNK1EMEN1KMT2ATP53
Hydrochloric Acid SCHEMBL8658738 1.00 BDKRB2 (0.50) BDKRB2CSNK1EMEN1KMT2ATP53
Hydrochloric Acid SCHEMBL5091313 1.00 BDKRB2 (0.50) BDKRB2CSNK1EMEN1KMT2ATP53
Hydrochloric Acid SCHEMBL5087769 1.00 BDKRB2 (0.50) BDKRB2CSNK1EMEN1KMT2ATP53
Hydrochloric Acid SCHEMBL11746968 1.00 BDKRB2 (0.50) BDKRB2CSNK1EMEN1KMT2ATP53
Hydrochloric Acid SCHEMBL678119 1.00 BDKRB2 (0.50) BDKRB2CSNK1EMEN1KMT2ATP53
Hydrochloric Acid SCHEMBL5084792 1.00 BDKRB2 (0.50) BDKRB2CSNK1EMEN1KMT2ATP53
Hydrochloric Acid SCHEMBL5085258 1.00 BDKRB2 (0.50) BDKRB2CSNK1EMEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9249262-B2 Curable organic polymer and method for production thereof, and curable composition containing the same KANEKA CORPORATION (JP) 2016-02-02 US disclosed
US-20110124734-A1 N-HALOGENATED AMINO ACID FORMULATIONS AND METHODS FOR CLEANING AND DISINFECTION ALCON RESEARCH, LTD. (US) 2011-05-26 US disclosed
EP-2139518-A1 N-HALOGENATED AMINO ACID FORMULATIONS Alcon Research, Ltd. (US) 2010-01-06 EP disclosed
EP-2139521-A1 N-HALOGENATED AMINO ACID FORMULATIONS AND METHODS FOR CLEANING AND DISINFECTION Alcon Research, Ltd. (US) 2010-01-06 EP disclosed
US-20090247712-A1 CURABLE ORGANIC POLYMER AND METHOD FOR PRODUCTION THEREOF, AND CURABLE COMPOSITION CONTAINING THE SAME KANEKA CORPORATION (JP) 2009-10-01 US disclosed
WO-2008134694-A1 N-HALOGENATED AMINO ACID FORMULATIONS AND METHODS FOR CLEANING AND DISINFECTION ALCON RESEARCH, LTD. (US) 2008-11-06 WO disclosed
US-20080275123-A1 N-HALOGENATED AMINO ACID FORMULATIONS ALCON RESEARCH, LTD. (US) 2008-11-06 US disclosed
WO-2008134687-A1 N-HALOGENATED AMINO ACID FORMULATIONS ALCON RESEARCH, LTD. (US) 2008-11-06 WO disclosed
US-20080275121-A1 N-HALOGENATED AMINO ACID FORMULATIONS AND METHODS FOR CLEANING AND DISINFECTION ALCON RESEARCH, LTD. (US) 2008-11-06 US disclosed
US-20080214386-A1 Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080275121-A1 N-HALOGENATED AMINO ACID FORMULATIONS AND METHODS FOR CLEANING AND DISINFECTION BCAT1, BCAT2, ASNS BDKRB2 3656/4885CSNK1E 1598/4885MEN1 3565/4885
US-20110124734-A1 N-HALOGENATED AMINO ACID FORMULATIONS AND METHODS FOR CLEANING AND DISINFECTION BCAT1, BCAT2, ASNS BDKRB2 3656/4885CSNK1E 1598/4885MEN1 3565/4885
US-20080275123-A1 N-HALOGENATED AMINO ACID FORMULATIONS BCAT1, BCAT2, SLC7A1 BDKRB2 2145/4885CSNK1E 2871/4885MEN1 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.