SCHEMBL17651765

SCHEMBL17651765

OCC(O)COc1c(F)c(F)c(-c2c3nc(c(-c4cccc(O)c4)c4[nH]c(c(O)c4O)c(-c4c(F)c(F)c(OCC(O)CO)c(F)c4F)c4nc(c(-c5cccc(O)c5)c5ccc2[nH]5)C=C4)C=C3)c(F)c1F

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PDE3B Q13370 1/20 0.32
▸ PDE3A Q14432 1/20 0.32
▸ P2RY12 Q9H244 1/20 0.32
▸ TERT O14746 1/20 0.31
▸ DHODH Q02127 1/20 0.31
▸ PIK3CG P48736 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17651771 0.95 TERT (0.34) PDE3BPDE3AP2RY12TERTDHODH
SCHEMBL17651803 0.95 TERT (0.34) PDE3BPDE3AP2RY12TERTDHODH
SCHEMBL31679222 0.95 TERT (0.34) PDE3BPDE3AP2RY12TERTDHODH
SCHEMBL31679251 0.95 TERT (0.34) PDE3BPDE3AP2RY12TERTDHODH
SCHEMBL17651782 0.92 — —
SCHEMBL17651791 0.92 — —
SCHEMBL19846930 0.90 DHODH (0.36) PDE3BPDE3AP2RY12TERTDHODH
SCHEMBL17659987 0.89 PDE3B (0.30) PDE3BPDE3AP2RY12TERTDHODH
SCHEMBL17660314 0.89 PDE3B (0.30) PDE3BPDE3AP2RY12TERTDHODH
SCHEMBL17660313 0.89 PDE3B (0.30) PDE3BPDE3AP2RY12TERTDHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12403127-B2 Specifically meso-substituted porphyrins and chlorins for photodynamic therapy BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2025-09-02 — — US disclosed
EP-3201201-B1 SPECIFICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2022-01-26 — — EP disclosed
US-10456375-B2 Specifically meso-substituted porphyrins and chlorins for photodynamic therapy BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2019-10-29 — — US disclosed
US-20180036284-A1 SPECIFICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2018-02-08 — — US disclosed
EP-3201201-A1 SPECIFICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY biolitec unternehmensbeteiligungs II AG (AT) 2017-08-09 — — EP disclosed
WO-2016051361-A1 SPECIFICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2016-04-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180036284-A1 SPECIFICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY DHPS, DDT, PPOX PDE3B 4843/4885PDE3A 4758/4885P2RY12 3948/4885
US-12403127-B2 Specifically meso-substituted porphyrins and chlorins for photodynamic therapy DHPS, DDT, PPOX PDE3B 4843/4885PDE3A 4758/4885P2RY12 3948/4885
US-10456375-B2 Specifically meso-substituted porphyrins and chlorins for photodynamic therapy DHPS, DDT, PPOX PDE3B 4843/4885PDE3A 4758/4885P2RY12 3948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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