SCHEMBL17651771

SCHEMBL17651771

OCC(O)COc1c(F)c(F)c(-c2c3nc(c(-c4cccc(O)c4)c4ccc([nH]4)c(-c4c(F)c(F)c(OCC(O)CO)c(F)c4F)c4nc(c(-c5cccc(O)c5)c5ccc2[nH]5)C=C4)C=C3)c(F)c1F

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 2/20 0.34
▸ PDE3B Q13370 1/20 0.34
▸ PDE3A Q14432 1/20 0.34
▸ P2RY12 Q9H244 1/20 0.34
▸ DHODH Q02127 1/20 0.34
▸ PIK3CG P48736 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ TOP1 P11387 1/20 0.32
▸ CYCS P99999 2/20 0.32
▸ ALOX5AP P20292 1/20 0.32
▸ FEN1 P39748 1/20 0.32
▸ AURKA O14965 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31679222 1.00 TERT (0.34) TERTPDE3BPDE3AP2RY12DHODH
SCHEMBL17651803 1.00 TERT (0.34) TERTPDE3BPDE3AP2RY12DHODH
SCHEMBL31679251 1.00 TERT (0.34) TERTPDE3BPDE3AP2RY12DHODH
SCHEMBL17651765 0.95 PDE3B (0.32) TERTPDE3BPDE3AP2RY12DHODH
SCHEMBL19846930 0.95 DHODH (0.36) TERTPDE3BPDE3AP2RY12DHODH
SCHEMBL17660121 0.94 PRMT5 (0.31) TERTPDE3BPDE3AP2RY12DHODH
SCHEMBL19855681 0.94 PIK3CG (0.32) TERTPDE3BPDE3AP2RY12DHODH
SCHEMBL24221242 0.93 TSHR (0.43) DHODHPIK3CGTSHRMAPK1
SCHEMBL17651792 0.93 PRMT5 (0.31) TERTPDE3BPDE3AP2RY12DHODH
SCHEMBL17651764 0.93 PIK3CG (0.32) TERTPDE3BPDE3AP2RY12DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12403127-B2 Specifically meso-substituted porphyrins and chlorins for photodynamic therapy BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2025-09-02 — — US disclosed
EP-3201201-B1 SPECIFICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2022-01-26 — — EP disclosed
EP-3201201-B1 SPECIFICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2022-01-26 — — EP disclosed
US-10456375-B2 Specifically meso-substituted porphyrins and chlorins for photodynamic therapy BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2019-10-29 — — US disclosed
US-10456375-B2 Specifically meso-substituted porphyrins and chlorins for photodynamic therapy BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2019-10-29 — — US disclosed
US-20180036284-A1 SPECIFICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2018-02-08 — — US disclosed
US-20180036284-A1 SPECIFICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2018-02-08 — — US disclosed
US-20180036284-A1 SPECIFICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2018-02-08 — — US disclosed
EP-3201201-A1 SPECIFICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY biolitec unternehmensbeteiligungs II AG (AT) 2017-08-09 — — EP disclosed
WO-2016051361-A1 SPECIFICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2016-04-07 — — WO disclosed
WO-2016051361-A1 SPECIFICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2016-04-07 — — WO disclosed
US-20150374714-A1 GENERATION OF FUNCTIONAL DENDRITIC CELLS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2015-12-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180036284-A1 SPECIFICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY DHPS, DDT, PPOX TERT 1760/4885PDE3B 4843/4885PDE3A 4758/4885
US-12403127-B2 Specifically meso-substituted porphyrins and chlorins for photodynamic therapy DHPS, DDT, PPOX TERT 1760/4885PDE3B 4843/4885PDE3A 4758/4885
US-20150374714-A1 GENERATION OF FUNCTIONAL DENDRITIC CELLS IFNG, MAVS, IFNAR1 TERT 4356/4885PDE3B 3999/4885PDE3A 3678/4885
US-10456375-B2 Specifically meso-substituted porphyrins and chlorins for photodynamic therapy DHPS, DDT, PPOX TERT 1760/4885PDE3B 4843/4885PDE3A 4758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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