SCHEMBL17652443

SCHEMBL17652443

N#CC1Cc2ccccc2N1Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MTNR1A P48039 9/20 0.40
▸ MTNR1B P49286 3/20 0.40
▸ GAA P10253 1/20 0.40
▸ SIGMAR1 Q99720 1/20 0.40
▸ LMNA P02545 1/20 0.39
▸ ALOX12 P18054 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ HDAC11 Q96DB2 2/20 0.38
▸ HDAC8 Q9BY41 2/20 0.38
▸ HDAC6 Q9UBN7 2/20 0.38
▸ HDAC9 Q9UKV0 1/20 0.38
▸ HDAC5 Q9UQL6 1/20 0.38
▸ PREP P48147 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17652452 0.85 MTNR1A (0.50) MTNR1AMTNR1BSIGMAR1POLBHDAC11
SCHEMBL4418509 0.76 GAA (0.61) GAALMNAALOX12MAPK1POLB
SCHEMBL11389829 0.74 MTNR1A (0.48) MTNR1AMTNR1BGAALMNAALOX12
SCHEMBL7554464 0.73 MTNR1A (0.47) MTNR1AMTNR1BGAALMNAALOX12
SCHEMBL27883632 0.73 MTNR1A (0.51) MTNR1AMTNR1BGAALMNAALOX12
SCHEMBL7554460 0.73 MTNR1A (0.47) MTNR1AMTNR1BGAALMNAALOX12
SCHEMBL7557182 0.73 MTNR1A (0.50) MTNR1AMTNR1BGAALMNAALOX12
SCHEMBL10759991 0.72 NOTUM (0.39) MTNR1AMTNR1BPOLB
SCHEMBL7555842 0.72 MTNR1A (0.40) MTNR1AMTNR1BGAALMNAALOX12
SCHEMBL7555837 0.72 MTNR1A (0.40) MTNR1AMTNR1BGAALMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3436500-B1 TWO PART CURABLE COMPOSITIONS HENKEL AG & CO KGAA (DE) 2024-08-07 — — EP disclosed
CN-109071786-B Two part curable composition 汉高知识产权控股有限责任公司 2021-09-14 — — CN disclosed
CN-106715559-B Curing accelerators for anaerobic curable compositions 汉高知识产权控股有限责任公司 2020-02-28 — — CN disclosed
CN-109071786-A two part curable composition 汉高知识产权控股有限责任公司 2018-12-21 — — CN disclosed
US-9969690-B2 Cure accelerators for anaerobic curable compositions Henkel IP & Holding GmbH (DE) 2018-05-15 — — US disclosed
EP-3201266-A1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2017-08-09 — — EP disclosed
US-20170174630-A1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2017-06-22 — — US disclosed
CN-106715559-A Cure accelerators for anaerobic curable compositions 汉高知识产权控股有限责任公司 2017-05-24 — — CN disclosed
WO-2016054124-A1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2016-04-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170174630-A1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS AHCY, AHCYL1, CAPG MTNR1A 3638/4885MTNR1B 4354/4885GAA 1976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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