Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PAM | P19021 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18657175 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL19687213 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL15457871 | 0.79 | GRIK1 (0.41) | ALDH1A1MAPK1CYP3A4TDP1 | |
| SCHEMBL13569657 | 0.78 | PAM (0.52) | ALDH1A1MAPK1PAM | |
| SCHEMBL24434964 | 0.71 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL13264504 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRMAPK1CYP3A4 | |
| SCHEMBL28198316 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRMAPK1CYP3A4 | |
| SCHEMBL12855366 | 0.71 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL20079988 | 0.71 | ALDH1A1 (0.36) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL20079993 | 0.70 | NPC1 (0.39) | ALDH1A1HSD17B10TP53CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9303127-B2 | Lignin extraction from lignocellulosics | COLORADO SCHOOL OF MINES (US) | 2016-04-05 | — | — | US | disclosed |