Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12855366 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TSHRTP53CYP3A4KDM4E | |
| SCHEMBL28249128 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHRTP53CYP3A4KDM4E | |
| SCHEMBL13100599 | 0.79 | NFE2L2 (0.52) | ALDH1A1SMN1; SMN2MAPTKMT2ACA2 | |
| SCHEMBL9461723 | 0.79 | CYP3A4 (0.65) | ALDH1A1TSHRTP53CYP3A4KDM4E | |
| SCHEMBL333123 | 0.79 | CYP3A4 (0.65) | ALDH1A1TSHRTP53CYP3A4KDM4E | |
| SCHEMBL7527708 | 0.79 | CYP3A4 (0.65) | ALDH1A1TSHRTP53CYP3A4KDM4E | |
| SCHEMBL13264504 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4LMNAHSD17B10 | |
| SCHEMBL28198316 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4LMNAHSD17B10 | |
| SCHEMBL27544851 | 0.76 | CYP3A4 (0.62) | ALDH1A1TSHRTP53CYP3A4KDM4E | |
| SCHEMBL18657175 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TSHRTP53CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | ALDH1A1 4817/4885TSHR 2467/4885TP53 2849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.