Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 5/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.42 |
| ▸ | BAX | Q07812 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19774489 | 0.85 | ESR2 (0.61) | ESR2MEN1KMT2AESR1LTA4H | |
| SCHEMBL11764231 | 0.76 | ESR2 (0.52) | ESR2MEN1KMT2AESR1LTA4H | |
| SCHEMBL27371981 | 0.76 | CA1 (0.61) | ESR2MEN1KMT2ALTA4HKDM4E | |
| SCHEMBL16422185 | 0.76 | ACHE (0.50) | MEN1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL27729163 | 0.74 | CYP2A6 (0.42) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL27971125 | 0.74 | LMNA (0.42) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL20112487 | 0.74 | TDP1 (0.52) | MEN1KMT2ANPC1ALDH1A1CYP3A4 | |
| SCHEMBL23735063 | 0.73 | CA2 (0.58) | KDM4ECA1CA2CA4CA5A | |
| SCHEMBL27986636 | 0.72 | NR1H2 (0.35) | NR1H2 | |
| SCHEMBL8154525 | 0.72 | CA1 (0.59) | KMT2AKDM4ENPC1ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760775-B2 | Steroids and protein-conjugates thereof | REGENERON PHARMACEUTICALS, INC. | 2023-09-19 | — | — | US | disclosed |
| US-20210040144-A1 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. | 2021-02-11 | — | — | US | disclosed |
| US-10711032-B2 | Steroids and protein-conjugates thereof | REGENERON PHARMACEUTICALS, INC. (US) | 2020-07-14 | — | — | US | disclosed |
| US-20180155389-A1 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. | 2018-06-07 | — | — | US | disclosed |
| EP-2778201-B1 | COLOURED COMPOSITION AND INK FOR INKJET RECORDING | FUJIFILM CORP (JP) | 2016-04-06 | — | — | EP | disclosed |
| CN-105473584-A | Thiophene- or furan-substituted isothiazoline compounds as pesticides | MERIAL LTD | 2016-04-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180155389-A1 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | SERPINA6, NR3C1, NR3C2 | ESR2 171/4885MEN1 2876/4885KMT2A 4571/4885 |
| US-10711032-B2 | Steroids and protein-conjugates thereof | SERPINA6, NR3C1, NR3C2 | ESR2 171/4885MEN1 2876/4885KMT2A 4571/4885 |
| US-20210040144-A1 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | SERPINA6, NR3C1, NR3C2 | ESR2 155/4885MEN1 2791/4885KMT2A 4548/4885 |
| US-11760775-B2 | Steroids and protein-conjugates thereof | SERPINA6, NR3C1, NR3C2 | ESR2 155/4885MEN1 2791/4885KMT2A 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.