SCHEMBL17655596

SCHEMBL17655596

Cc1ccccc1C(=O)c1ccc(Sc2ccc(C(=O)/C(CCC3CCCCC3)=N/O[C@@H](O)c3ccccc3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
L3MBTL1 Q9Y468 3/20 0.34
KLK7 P49862 4/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 2/20 0.33
LDLR P01130 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
OPRK1 P41145 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17540459 0.85 KMT2A (0.39) FFAR1MEN1KMT2AL3MBTL1SMN1; SMN2
SCHEMBL19919517 0.79 ALDH1A1 (0.35) L3MBTL1LMNANPC1RAB9AALDH1A1
SCHEMBL22776405 0.78 FFAR1 (0.45) FFAR1MEN1KMT2ALDLRNPC1
SCHEMBL17540461 0.76 L3MBTL1 (0.44) MEN1KMT2AL3MBTL1KLK7SMN1; SMN2
SCHEMBL19795433 0.75 MEN1 (0.43) MEN1KMT2AL3MBTL1KLK7SMN1; SMN2
SCHEMBL17069995 0.75 MEN1 (0.43) MEN1KMT2AL3MBTL1KLK7SMN1; SMN2
SCHEMBL17069999 0.74 L3MBTL1 (0.44) MEN1KMT2AL3MBTL1KLK7SMN1; SMN2
SCHEMBL17540464 0.74 KMT2A (0.50) MEN1KMT2AL3MBTL1SMN1; SMN2LMNA
SCHEMBL17070003 0.73 L3MBTL1 (0.43) MEN1KMT2AL3MBTL1KLK7SMN1; SMN2
SCHEMBL17540444 0.73 L3MBTL1 (0.43) MEN1KMT2AL3MBTL1KLK7SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3002632-A1 ACRYLIC PHOTOCURABLE COMPOSITION Changzhou Tronly Advanced Electronics Materials Co., Ltd. (CN) 2016-04-06 EP disclosed