Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.48 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.48 |
| ▸ | ABAT | P80404 | 1/20 | 0.48 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22824489 | 0.91 | ALDH1A1 (0.46) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL96635 | 0.89 | ALDH1A1 (0.59) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL16619850 | 0.89 | ALDH1A1 (0.59) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| Hydrochloric Acid SCHEMBL23711567 | 0.87 | ALDH1A1 (0.57) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL30541333 | 0.84 | TUBB4A (0.51) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL20545861 | 0.84 | TUBB4A (0.51) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL26100046 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL5045913 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL5044810 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL24016983 | 0.81 | TPMT (0.61) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11384195-B2 | Difunctional biphenyl compounds, preparation, and uses | ARIANEGROUP SAS (FR) | 2022-07-12 | — | — | US | disclosed |
| EP-3749637-B1 | DIFUNCTIONAL BIPHENYL COMPOUNDS, PREPARATION, AND USES | ARIANEGROUP SAS (FR) | 2021-11-10 | — | — | EP | disclosed |
| US-20200399419-A1 | DIFUNCTIONAL BIPHENYL COMPOUNDS, PREPARATION, AND USES | ARIANEGROUP SAS (FR) | 2020-12-24 | — | — | US | disclosed |
| WO-2019155169-A1 | DIFUNCTIONAL BIPHENYL COMPOUNDS, PREPARATION, AND USES | ARIANEGROUP SAS (FR) | 2019-08-15 | — | — | WO | disclosed |
| US-20190032098-A1 | PROCESS FOR PREPARING BIPHENYL COMPOUNDS | UNIV BORDEAUX (FR) | 2019-01-31 | — | — | US | disclosed |
| US-20170240937-A1 | NEW PROCESS FOR PREPARING BIPHENYL COMPOUNDS | UNIVERSITÉ DE BORDEAUX (FR) | 2017-08-24 | — | — | US | disclosed |
| US-20170240937-A1 | NEW PROCESS FOR PREPARING BIPHENYL COMPOUNDS | UNIVERSITÉ DE BORDEAUX (FR) | 2017-08-24 | — | — | US | disclosed |
| WO-2016050988-A1 | NEW PROCESS FOR PREPARING BIPHENYL COMPOUNDS | UNIVERSITÉ DE BORDEAUX (FR) | 2016-04-07 | — | — | WO | disclosed |
| EP-3002333-A1 | Process for preparing biphenyl compounds | Université de Bordeaux (FR) | 2016-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190032098-A1 | PROCESS FOR PREPARING BIPHENYL COMPOUNDS | CYP1B1, CYP1A1, CYP1A2 | ALDH1A1 133/4885TSHR 3579/4885HPGD 743/4885 |
| US-20170240937-A1 | NEW PROCESS FOR PREPARING BIPHENYL COMPOUNDS | CYP1B1, CYP1A1, CYP1A2 | ALDH1A1 85/4885TSHR 4136/4885HPGD 647/4885 |
| US-20200399419-A1 | DIFUNCTIONAL BIPHENYL COMPOUNDS, PREPARATION, AND USES | ALK, ALKBH3, AHR | ALDH1A1 24/4885TSHR 3337/4885HPGD 3155/4885 |
| US-11384195-B2 | Difunctional biphenyl compounds, preparation, and uses | ALK, ALKBH3, AHR | ALDH1A1 24/4885TSHR 3337/4885HPGD 3155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.