Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96635 | 0.87 | ALDH1A1 (0.59) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL16619850 | 0.87 | ALDH1A1 (0.59) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| Hydrochloric Acid SCHEMBL23711567 | 0.85 | ALDH1A1 (0.57) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL17655658 | 0.82 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL24756113 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL9888329 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL5045277 | 0.80 | FDPS (0.46) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL5045913 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL26100046 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL1766183 | 0.78 | TUBB1 (0.50) | ALDH1A1TSHRHPGDTDP1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062905-A2 | CHROMENE DERIVATIVES AND THEIR ANALOGA AS WNT PATHWAY ANTAGONISTS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DKFZ) (DE) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012062901-A2 | CHROMENE DERIVATIVES AND THEIR ANALOGA AS WNT PATHWAY ANTAGONISTS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DKFZ) (DE) | 2012-05-18 | — | — | WO | disclosed |
| EP-1392683-B1 | SUBSTITUTED 4H-CHROMENES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THEIR USE AS ANTICANCER AGENTS | CYTOVIA INC (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2007065032-A2 | COMPOUNDS AND METHODS FOR INHIBITING VIRAL ENTRY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-07 | — | — | WO | disclosed |