SCHEMBL17656805

SCHEMBL17656805

CC(C)(C)c1ccc(N(c2cccc(-c3cccc4ccccc34)c2)c2ccc3c(c2)C2(c4ccccc4-c4ccccc42)c2c-3c3ccccc3c3cc(N(c4ccc(C(C)(C)C)cc4)c4cccc(-c5cccc6ccccc56)c4)ccc23)cc1

nearest known ligand 0.30

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NR1I2 O75469 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ ADRA2A P08913 1/20 0.30
▸ CYP2D6 P10635 1/20 0.30
▸ ACHE P22303 1/20 0.30
▸ SLC6A2 P23975 1/20 0.30
▸ HTR2A P28223 1/20 0.30
▸ SLC6A4 P31645 1/20 0.30
▸ KCNH2 Q12809 1/20 0.30
▸ SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10331229 0.92 CHRNA1 (0.32) SLC6A2SLC6A4
SCHEMBL17656817 0.92 PDK2 (0.31) —
SCHEMBL17656818 0.91 — —
SCHEMBL17656811 0.91 PDK2 (0.32) —
SCHEMBL17656820 0.90 CHRNA1 (0.32) SLC6A2SLC6A4
SCHEMBL17656801 0.90 PDK2 (0.31) —
SCHEMBL20736293 0.86 NR1I2 (0.32) NR1I2LMNAADRA2ACYP2D6ACHE
SCHEMBL24817303 0.85 CA12 (0.34) SLC6A2SLC6A4
SCHEMBL20736273 0.85 LMNA (0.31) NR1I2LMNAADRA2ACYP2D6ACHE
SCHEMBL17656815 0.84 PDK2 (0.31) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3524661-B1 ORGANIC LIGHT-EMITTING DEVICE HAVING LONG LIFE, LOW VOLTAGE AND HIGH EFFICIENCY SFC CO LTD (KR) 2022-06-01 — — EP disclosed
US-20210288266-A1 ORGANIC LIGHT-EMITTING DIODE HAVING LONG LIFESPAN, LOW VOLTAGE, AND HIGH EFFICIENCY PROPERTY SFC CO., LTD. (KR) 2021-09-16 — — US disclosed
EP-3524661-A1 ORGANIC LIGHT-EMITTING DEVICE HAVING LONG LIFE, LOW VOLTAGE AND HIGH EFFICIENCY SFC Co., Ltd. (KR) 2019-08-14 — — EP disclosed
US-9653689-B2 Condensed-cyclic compound and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-05-16 — — US disclosed
US-9653689-B2 Condensed-cyclic compound and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-05-16 — — US disclosed
US-20160099411-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SFC CO., LTD. (KR) 2016-04-07 — — US disclosed
US-20160099411-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SFC CO., LTD. (KR) 2016-04-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210288266-A1 ORGANIC LIGHT-EMITTING DIODE HAVING LONG LIFESPAN, LOW VOLTAGE, AND HIGH EFFICIENCY PROPERTY CYBA, CRY2, AOC2 NR1I2 3347/4885LMNA 122/4885ADRA2A 1181/4885
US-20160099411-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME CRY1, CCNT1, CCNE2 NR1I2 352/4885LMNA 2156/4885ADRA2A 1842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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