SCHEMBL17658588

SCHEMBL17658588

OBOc1ccc(N(c2ccccc2)c2cccc3c2oc2ccccc23)cc1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 3/20 0.34
▸ LMNA P02545 1/20 0.33
▸ MAPT P10636 2/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ MAOA P21397 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17658595 0.89 ALOX5 (0.37) ALOX5HDAC8
SCHEMBL14295291 0.85 ALOX5 (0.40) ALOX5LMNAMAPTNPC1MAOA
SCHEMBL26815441 0.84 ALOX5 (0.47) ALOX5LMNAHDAC8
SCHEMBL15730662 0.84 ALOX5 (0.39) ALOX5LMNAMAPTNPC1MAOA
SCHEMBL15306316 0.84 ALOX5 (0.41) ALOX5LMNAMAPTNPC1MAOA
SCHEMBL17716679 0.81 ALOX5 (0.42) ALOX5LMNAMAPTNPC1MAOA
SCHEMBL6372493 0.81 ALOX5 (0.42) ALOX5LMNAMAPTNPC1MAOA
SCHEMBL14295254 0.81 ALOX5 (0.42) ALOX5LMNAMAPTNPC1MAOA
SCHEMBL15178580 0.81 ALOX5 (0.41) ALOX5LMNAMAPTNPC1MAOA
SCHEMBL29294345 0.81 CNR2 (0.32) LMNANPC1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9923147-B2 Organic light emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-20 — — US disclosed
US-9856243-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-01-02 — — US disclosed
US-20160329501-A1 ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-11-10 — — US disclosed
US-20160099423-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160099423-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, MCM4 ALOX5 2708/4885LMNA 1368/4885MAPT 1667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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