SCHEMBL17658595

SCHEMBL17658595

OBOc1ccc(N(c2ccccc2-c2ccccc2)c2cccc3c2oc2ccccc23)cc1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 3/20 0.37
▸ GGPS1 O95749 1/20 0.33
▸ HDAC8 Q9BY41 1/20 0.32
▸ CDC14B O60729 1/20 0.31
▸ CDC14A Q9UNH5 1/20 0.31
▸ PRMT5 O14744 1/20 0.31
▸ WDR77 Q9BQA1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17658588 0.89 ALOX5 (0.34) ALOX5HDAC8
SCHEMBL16632552 0.85 HDAC8 (0.39) ALOX5HDAC8
SCHEMBL26815441 0.85 ALOX5 (0.47) ALOX5GGPS1HDAC8CDC14BCDC14A
SCHEMBL17322345 0.85 LMNA (0.39) —
SCHEMBL21214774 0.82 ALOX5 (0.46) ALOX5GGPS1CDC14BCDC14A
SCHEMBL16632993 0.82 CDC14B (0.36) ALOX5GGPS1HDAC8CDC14BCDC14A
SCHEMBL17322306 0.82 ALOX5 (0.40) ALOX5GGPS1CDC14BCDC14A
SCHEMBL16641966 0.82 ALOX5 (0.39) ALOX5GGPS1CDC14BCDC14A
SCHEMBL24370266 0.81 ALOX5 (0.43) ALOX5GGPS1CDC14BCDC14A
SCHEMBL24370077 0.81 ALOX5 (0.43) ALOX5GGPS1CDC14BCDC14A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9923147-B2 Organic light emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-20 — — US disclosed
US-9856243-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-01-02 — — US disclosed
US-9741939-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-22 — — US disclosed
US-20160329501-A1 ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-11-10 — — US disclosed
US-20160118593-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 — — US disclosed
US-20160099423-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160099423-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, MCM4 ALOX5 2708/4885GGPS1 365/4885HDAC8 2925/4885
US-20160118593-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNA1, CCNT1 ALOX5 2773/4885GGPS1 755/4885HDAC8 3578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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