Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17658992 | 0.83 | MRGPRX4 (0.40) | KDM4EALDH1A1SMN1; SMN2TDP1NPC1 | |
| SCHEMBL13744509 | 0.77 | DRD2 (0.55) | HRH3KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL3720686 | 0.76 | KDM4E (0.54) | HRH3KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL21558822 | 0.74 | CYP2C19 (0.67) | KDM4EALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL9650233 | 0.74 | SMN1; SMN2 (0.45) | SMN1; SMN2THRATHRBNPC1HPGD | |
| SCHEMBL3785500 | 0.73 | SMN1; SMN2 (0.59) | KDM4EALDH1A1SMN1; SMN2TDP1THRA | |
| SCHEMBL6816572 | 0.73 | KDM4E (0.53) | HRH3KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL18998218 | 0.73 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2TDP1THRA | |
| SCHEMBL9671156 | 0.72 | KDM4E (0.83) | HRH3KDM4EALDH1A1SMN1; SMN2LSS | |
| SCHEMBL2205258 | 0.72 | ALDH1A1 (0.54) | HRH3KDM4EALDH1A1SMN1; SMN2LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |