Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | QDPR | P09417 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29236372 | 0.84 | GAA (0.41) | ALDH1A1HSP90AA1LMNAGAASMN1; SMN2 | |
| SCHEMBL17659681 | 0.84 | GAA (0.41) | ALDH1A1HSP90AA1LMNAGAASMN1; SMN2 | |
| SCHEMBL19381709 | 0.81 | GFER (0.53) | ALDH1A1CASP6GFERLMNAGAA | |
| SCHEMBL3574977 | 0.81 | ALDH1A1 (0.48) | ALDH1A1CASP6GFERNCF1LMNA | |
| SCHEMBL19381318 | 0.80 | GFER (0.51) | ALDH1A1CASP6GFERLMNAGAA | |
| SCHEMBL17658993 | 0.80 | ESR2 (0.54) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL3801245 | 0.79 | GAA (0.65) | ALDH1A1NCF1LMNAGAASMN1; SMN2 | |
| SCHEMBL17659051 | 0.79 | MEN1 (0.45) | ALDH1A1GAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL17659123 | 0.79 | DRD2 (0.51) | ALDH1A1HSP90AA1HSP90AB1GAAMAPT | |
| SCHEMBL17659041 | 0.78 | ALOX15 (0.58) | ALDH1A1LMNAGAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016051799-A1 | 2-AMINOHYDROQUINONE DERIVATIVE AND TAU AGGREGATION INHIBITOR | 学校法人同志社 | 2016-04-07 | — | — | WO | disclosed |