Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | DRD1 | P21728 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD5 | P21918 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10380337 | 1.00 | HRH1 (0.54) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL17660557 | 1.00 | HRH1 (0.54) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL30481559 | 1.00 | HRH1 (0.54) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL23697046 | 0.89 | LMNA (0.57) | HRH1DRD2DRD1DRD4DRD5 | |
| N-Methylpiperidine SCHEMBL25219666 | 0.87 | HRH1 (0.57) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL17660559 | 0.86 | HRH1 (0.57) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL15257126 | 0.83 | HRH1 (0.54) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL28249875 | 0.83 | HRH1 (0.54) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL11335418 | 0.82 | MEN1 (0.51) | LMNAHPGDCYP1A2CYP3A4 | |
| SCHEMBL15255817 | 0.82 | HSPA5 (0.52) | LMNACYP1A2TSHRADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528863-B | Method for preparing high-purity 1- (1- (2-benzyl phenoxy) propan-2-yl) -2-methylpiperidine single isomer | VS 药物技术公司 | 2025-04-08 | — | — | CN | disclosed |
| US-12227477-B2 | Method for preparing single isomer of 1-(1-(2-benzylphenoxy)propan-2-yl)-2-methylpiperidine in high-purity | VSpharmtech (KR) | 2025-02-18 | — | — | US | disclosed |
| US-20240174609-A1 | METHOD FOR PREPARING SINGLE ISOMER OF 1-(1-(2-BENZYLPHENOXY)PROPAN-2-YL)-2-METHYLPIPERIDINE IN HIGH-PURITY | VSpharmtech (KR) | 2024-05-30 | — | — | US | disclosed |
| CN-112166106-B | Cancer metastasis inhibitors by inhibiting cancer cell migration and invasion | VS药物技术公司 | 2024-05-24 | — | — | CN | disclosed |
| US-11945779-B2 | Inhibitors of cancer metastasis through inhibiting migration and invasion of cancer cells | VSpharmtech (KR) | 2024-04-02 | — | — | US | disclosed |
| CN-116528863-A | Method for preparing high-purity 1- (1- (2-benzyl phenoxy) propan-2-yl) -2-methylpiperidine single isomer | VS 药物技术公司 | 2023-08-01 | — | — | CN | disclosed |
| EP-4212512-A1 | PREPARATION METHOD FOR HIGH PURITY 1-(1-(2-BENZYL PHENOXY)PROPAN-2-YL)-2-METHYLPIPERIDINE SINGLE ISOMER | VSpharmtech Inc. (KR) | 2023-07-19 | — | — | EP | disclosed |
| EP-4212512-A1 | PREPARATION METHOD FOR HIGH PURITY 1-(1-(2-BENZYL PHENOXY)PROPAN-2-YL)-2-METHYLPIPERIDINE SINGLE ISOMER | VSpharmtech Inc. (KR) | 2023-07-19 | — | — | EP | disclosed |
| WO-2023101115-A1 | PREPARATION METHOD FOR HIGH PURITY 1-(1-(2-BENZYL PHENOXY)PROPAN-2-YL)-2-METHYLPIPERIDINE SINGLE ISOMER | 주식회사 브이에스팜텍 | 2023-06-08 | — | — | WO | disclosed |
| US-20210246105-A1 | INHIBITORS OF CANCER METASTASIS THROUGH INHIBITING MIGRATION AND INVASION OF CANCER CELLS | VSpharmtech (KR) | 2021-08-12 | — | — | US | disclosed |
| US-20210246105-A1 | INHIBITORS OF CANCER METASTASIS THROUGH INHIBITING MIGRATION AND INVASION OF CANCER CELLS | VSpharmtech (KR) | 2021-08-12 | — | — | US | disclosed |
| EP-3774730-A1 | INHIBITORS OF CANCER METASTASIS THROUGH INHIBITING MIGRATION AND INVASION OF CANCER CELLS | Korea Research Institute of Bioscience and Biotechnology (KR) | 2021-02-17 | — | — | EP | disclosed |
| US-20160095845-A1 | COMPOSITION COMPRISING (S)-(-)-BENPROPERINE FOR PREVENTING OR TREATING CANCER | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2016-04-07 | — | — | US | disclosed |
| US-20160095845-A1 | COMPOSITION COMPRISING (S)-(-)-BENPROPERINE FOR PREVENTING OR TREATING CANCER | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2016-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12227477-B2 | Method for preparing single isomer of 1-(1-(2-benzylphenoxy)propan-2-yl)-2-methylpiperidine in high-purity | MBD2, PDE1C, NPEPPS | HRH1 1172/4885DRD2 25/4885DRD1 42/4885 |
| US-20210246105-A1 | INHIBITORS OF CANCER METASTASIS THROUGH INHIBITING MIGRATION AND INVASION OF CANCER CELLS | MMP9, MIF, MMP11 | HRH1 3220/4885DRD2 4656/4885DRD1 4678/4885 |
| US-20160095845-A1 | COMPOSITION COMPRISING (S)-(-)-BENPROPERINE FOR PREVENTING OR TREATING CANCER | BRCA1, MME, COMT | HRH1 1674/4885DRD2 543/4885DRD1 2129/4885 |
| US-11945779-B2 | Inhibitors of cancer metastasis through inhibiting migration and invasion of cancer cells | MMP9, MIF, MMP11 | HRH1 3220/4885DRD2 4656/4885DRD1 4678/4885 |
| US-20240174609-A1 | METHOD FOR PREPARING SINGLE ISOMER OF 1-(1-(2-BENZYLPHENOXY)PROPAN-2-YL)-2-METHYLPIPERIDINE IN HIGH-PURITY | MBD2, PDE1C, NPEPPS | HRH1 1172/4885DRD2 25/4885DRD1 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.