Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CHKA | P35790 | 1/20 | 0.56 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16513403 | 0.84 | CA2 (0.39) | CA2CHKASMARCA2SMARCA4MEN1 | |
| SCHEMBL1660333 | 0.84 | CA2 (0.39) | CA2CHKASMARCA2SMARCA4MEN1 | |
| SCHEMBL1661082 | 0.82 | CA2 (0.38) | CA2CHKAMEN1KMT2AAAK1 | |
| SCHEMBL24136814 | 0.82 | CA2 (0.38) | CA2CHKAMEN1KMT2A | |
| SCHEMBL27264896 | 0.82 | CA2 (0.68) | CA2CHKASMARCA2SMARCA4LOXL2 | |
| SCHEMBL16532258 | 0.80 | CA2 (0.36) | CA2CHKAMEN1KMT2AAAK1 | |
| SCHEMBL29416323 | 0.76 | NPC1 (0.33) | CA2CHKAMEN1KMT2ANPC1 | |
| SCHEMBL1661897 | 0.76 | NPC1 (0.33) | CA2CHKAMEN1KMT2ANPC1 | |
| SCHEMBL16513728 | 0.74 | NPC1 (0.33) | CA2CHKAMEN1KMT2ANPC1 | |
| SCHEMBL1660874 | 0.73 | NPC1 (0.35) | MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 407 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124475-B | Pyrimidine derivative and preparation method and application thereof | 贵阳学院 | 2023-11-10 | — | — | CN | claimed |
| CN-115124475-A | Pyrimidine derivative and preparation method and application thereof | 贵阳学院 | 2022-09-30 | — | — | CN | claimed |
| CN-102887860-B | Preparation method of 4-chloro-6-trifluoromethylpyrimidine type compound | SHANGHAI TITAN TECHNOLOGY CO LTD | 2015-07-01 | — | — | CN | claimed |
| CN-102887860-A | Preparation method of 4-chloro-6-trifluoromethylpyrimidine type compound | SHANGHAI TITAN TECHNOLOGY CO LTD | 2013-01-23 | — | — | CN | claimed |
| CN-117126147-B | Pyrimidine substituted 1,3, 4-oxadiazole derivative, preparation method and application | 贵阳学院 | 2026-05-15 | — | — | CN | disclosed |
| WO-2026101698-A1 | HEPCIDIN MIMETIC COMPOUNDS AND USES THEREOF | PROTAGONIST THERAPEUTICS, INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| EP-4735445-A1 | KRAS MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2026-05-06 | — | — | EP | disclosed |
| EP-4735453-A1 | KRAS MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2026-05-06 | — | — | EP | disclosed |
| US-20260083129-A1 | PYRAZOLE AMIDE INSECTICIDES | FMC CORP (US) | 2026-03-26 | — | — | US | disclosed |
| EP-4695260-A1 | KRAS MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2026-02-18 | — | — | EP | disclosed |
| US-12545682-B2 | Heterocyclic derivatives as P2X7 receptor antagonists | BREYE THERAPEUTICS APS (DK) | 2026-02-10 | — | — | US | disclosed |
| EP-4680609-A1 | KRAS MODULATORS AND USES THEREOF | Quanta Therapeutics, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2003004474-A1 | PESTICIDALLY ACTIVE AMINOACETONITRILES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-01-16 | — | — | WO | disclosed |
| WO-2002038569-A1 | IMIDAZO-PYRIMIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2002-05-16 | — | — | WO | disclosed |
| EP-0758321-B1 | 3-SUBSTITUTED PYRIDINE COMPOUNDS AND DERIVATIVES THEREOF AS HERBICIDES | ZENECA LTD (GB) | 1999-04-21 | — | — | EP | disclosed |
| US-5763357-A | HERBICIDES | ZENECA LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| US-5714438-A | PRE- AND POSTEMERGENCE HERBICIDES; BRAOADLEAF PLANTS AND GRASSES | ZENECA LIMITED (GB) | 1998-02-03 | — | — | US | disclosed |
| EP-0758321-A1 | 3-SUBSTITUTED PYRIDINE COMPOUNDS AND DERIVATIVES THEREOF AS HERBICIDES | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| US-5595958-A | HERBICIDES | ZENECA LIMITED (GB) | 1997-01-21 | — | — | US | disclosed |
| WO-1995029893-A1 | 3-SUBSTITUTED PYRIDINE COMPOUNDS AND DERIVATIVES THEREOF AS HERBICIDES | ZENECA LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260083129-A1 | PYRAZOLE AMIDE INSECTICIDES | CBR3, CBR1, NOX3 | CA2 2044/4885CHKA 1594/4885SMARCA2 4754/4885 |
| US-12545682-B2 | Heterocyclic derivatives as P2X7 receptor antagonists | P2RX7, P2RX3, P2RX1 | CA2 633/4885CHKA 1489/4885SMARCA2 4760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.