Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17664763 | 0.91 | MAPT (0.43) | MAPTKDM4EHPGDNLRP1ALDH1A1 | |
| SCHEMBL17663550 | 0.90 | MAPT (0.39) | MAPTKDM4EHPGDNLRP1ALDH1A1 | |
| SCHEMBL17663544 | 0.84 | CYP1A2 (0.38) | MAPTKDM4EHPGDTDP1ALDH1A1 | |
| SCHEMBL4642147 | 0.76 | CA1 (0.37) | MAPTKDM4ETDP1ALDH1A1KMT2A | |
| SCHEMBL4642224 | 0.76 | VCAM1 (0.40) | MAPTKDM4ETDP1ALDH1A1KMT2A | |
| SCHEMBL17662464 | 0.75 | KMT2A (0.36) | MAPTALDH1A1KMT2ALMNAGAA | |
| SCHEMBL4643898 | 0.75 | CA1 (0.36) | MAPTKDM4EHPGDTDP1ALDH1A1 | |
| SCHEMBL17662458 | 0.75 | ALDH1A1 (0.34) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL348786 | 0.74 | CA1 (0.41) | MAPTKDM4ETDP1ALDH1A1KMT2A | |
| SCHEMBL4641868 | 0.73 | VCAM1 (0.43) | MAPTKDM4EHPGDTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016050209-A1 | HETEROFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE, PREPARATION METHOD, AND BIO-RELATED SUBSTANCE | 厦门赛诺邦格生物科技有限公司 | 2016-04-07 | — | — | WO | disclosed |
| WO-2016050208-A1 | BIO-RELATED SUBSTANCE MODIFIED BY MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE | 厦门赛诺邦格生物科技有限公司 | 2016-04-07 | — | — | WO | disclosed |