Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDT | P30046 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17664233 | 0.93 | MLYCD (0.53) | KDM4ENPSR1MLYCDMEN1KMT2A | |
| SCHEMBL23447432 | 0.85 | MLYCD (0.58) | DDTKDM4ENPSR1MLYCDMEN1 | |
| SCHEMBL17664337 | 0.84 | LMNA (0.51) | HTTNPSR1MAOAMAOBMEN1 | |
| SCHEMBL17664237 | 0.81 | CNR1 (0.58) | HTTKDM4ENPSR1MAOAMAOB | |
| SCHEMBL17664230 | 0.80 | LMNA (0.52) | MEN1KMT2AGAAATG4BLMNA | |
| SCHEMBL23447438 | 0.80 | SMN1; SMN2 (0.68) | DDTHTTMEN1KMT2ALMNA | |
| SCHEMBL17664339 | 0.79 | PTPN1 (0.41) | DDTHTTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17664223 | 0.77 | ATG4B (0.49) | KDM4ENPSR1MAOAMAOBMLYCD | |
| SCHEMBL24713109 | 0.77 | MLYCD (0.67) | KDM4ENPSR1MLYCDMEN1KMT2A | |
| SCHEMBL17664299 | 0.76 | HTT (0.60) | HTTKDM4ENPSR1MAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016049774-A1 | UREA AND BIS-UREA BASED COMPOUNDS AND ANALOGUES THEREOF USEFUL IN THE TREATMENT OF ANDROGEN RECEPTOR MEDIATED DISEASES OR DISORDERS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2016-04-07 | — | — | WO | disclosed |