Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PPIB | P23284 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | PPIG | Q13427 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17664233 | 0.88 | MLYCD (0.53) | LMNAALDH1A1MAPTMEN1HSP90AA1 | |
| SCHEMBL17664230 | 0.84 | LMNA (0.52) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17664338 | 0.84 | DDT (0.53) | LMNAALDH1A1MAPTMEN1HSP90AA1 | |
| SCHEMBL17664237 | 0.79 | CNR1 (0.58) | LMNAMAPTMEN1HSP90AA1PKM | |
| SCHEMBL17664340 | 0.77 | MEN1 (0.55) | LMNAMAPTMEN1HSP90AA1PKM | |
| SCHEMBL17664299 | 0.76 | HTT (0.60) | LMNAALDH1A1MAPTMEN1HSP90AA1 | |
| SCHEMBL17664301 | 0.75 | KDM4E (0.57) | LMNAMAPTMEN1HSP90AA1PKM | |
| SCHEMBL17664313 | 0.75 | MAPT (0.64) | LMNAALDH1A1MAPTMEN1HSP90AA1 | |
| SCHEMBL17664350 | 0.73 | CNR1 (0.57) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17664223 | 0.73 | ATG4B (0.49) | LMNAALDH1A1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016049774-A1 | UREA AND BIS-UREA BASED COMPOUNDS AND ANALOGUES THEREOF USEFUL IN THE TREATMENT OF ANDROGEN RECEPTOR MEDIATED DISEASES OR DISORDERS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2016-04-07 | — | — | WO | disclosed |