Sugi Predict

Sugi Predict / Compounds / SCHEMBL1766450

SCHEMBL1766450

SCHEMBL1766450

CN(C(=O)c1ccccc1)c1cccc(C(=O)Nc2c(I)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2C(F)(F)F)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR1H3 Q13133 2/20 0.42
▸ NR1H2 P55055 1/20 0.42
▸ RXFP1 Q9HBX9 1/20 0.39
▸ LMNA P02545 2/20 0.38
▸ GAA P10253 1/20 0.38
▸ HDAC1 Q13547 1/20 0.38
▸ HDAC8 Q9BY41 1/20 0.38
▸ HDAC6 Q9UBN7 1/20 0.38
▸ MAPT P10636 4/20 0.38
▸ KCNJ11 Q14654 1/20 0.38
▸ KCNK3 O14649 1/20 0.37
▸ ALDH1A1 P00352 3/20 0.37
▸ POLQ O75417 2/20 0.37
▸ HTT P42858 1/20 0.37
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ KDM4E B2RXH2 2/20 0.36
▸ HPGD P15428 2/20 0.36
▸ ALOX15 P16050 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29427424 1.00 NR1H3 (0.42) NR1H3NR1H2RXFP1LMNAGAA
SCHEMBL1766423 0.95 NR1H3 (0.40) NR1H3NR1H2RXFP1LMNAGAA
SCHEMBL1766685 0.94 MAPT (0.41) NR1H3NR1H2RXFP1GAAHDAC1
SCHEMBL1766411 0.93 NR1H3 (0.46) NR1H3NR1H2RXFP1LMNAGAA
SCHEMBL1766769 0.92 MAPT (0.41) RXFP1LMNAMAPTKCNJ11KCNK3
SCHEMBL1766330 0.90 SIRT2 (0.39) NR1H3RXFP1LMNAKCNJ11
SCHEMBL1767108 0.90 RXFP1 (0.42) RXFP1LMNAGAAMAPTKCNJ11
SCHEMBL1766457 0.90 MAPT (0.37) RXFP1GAAMAPTKCNJ11ALDH1A1
SCHEMBL1767292 0.89 MAPT (0.39) NR1H3NR1H2RXFP1GAAHDAC1
SCHEMBL1766361 0.89 ABCB1 (0.44) RXFP1LMNAKCNK3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839214-B2 Fungicidal mixture comprising substituted pyridines BASF SE (DE) 2023-12-12 — — US claimed
CN-116076518-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-09 — — CN claimed
EP-3978504-A1 CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDINE DERIVATIVES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2022-04-06 — — EP claimed
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF BASF SE (DE) 2022-02-17 — — US claimed
EP-3942933-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF Agrochemical Products B.V. (NL) 2022-01-26 — — EP claimed
CN-108289456-B Mixture of cis-jasmone and bacillus amyloliquefaciens 巴斯夫欧洲公司 2022-01-11 — — CN claimed
EP-3601298-B1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2021-12-01 — — EP claimed
US-20210355139-A1 Pyrimidinium Compounds and Their Mixtures for Combating Animal Pests BASF SE (DE) 2021-11-18 — — US claimed
CN-113367135-A Agricultural mixtures comprising carboxamide compounds 巴斯夫农业化学品有限公司 2021-09-10 — — CN claimed
CN-113303339-A Mixture of cis-jasmone and bacillus amyloliquefaciens 巴斯夫欧洲公司 2021-08-27 — — CN claimed
EP-3057418-A1 INSECTICIDAL ACTIVE MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF Agrochemical Products, B.V. (NL) 2016-08-24 — — EP claimed
EP-3057420-A1 USE OF PESTICIDAL ACTIVE CARBOXAMIDE DERIVATIVE IN SOIL AND SEED APPLICATION AND TREATMENT METHODS BASF Agrochemical Products B.V. (NL) 2016-08-24 — — EP claimed
WO-2016128261-A2 PESTICIDAL MIXTURE COMPRISING A PYRAZOLE COMPOUND, AN INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2016-08-18 — — WO claimed
US-20160227772-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2016-08-11 — — US claimed
US-20160227771-A1 Insecticidal Active Mixtures Comprising Carboxamide Compound BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2016-08-11 — — US claimed
WO-2016079043-A1 PESTICIDAL COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND BASF Agro B.V. (NL) 2016-05-26 — — WO claimed
WO-2016059240-A1 METHOD AND PESTICIDAL MIXTURES FOR CONTROLLING PENTATOMIDAE PESTS BASF SE (DE) 2016-04-21 — — WO claimed
WO-2015055757-A1 USE OF PESTICIDAL ACTIVE CARBOXAMIDE DERIVATIVE IN SOIL AND SEED APPLICATION AND TREATMENT METHODS BASF SE (DE) 2015-04-23 — — WO claimed
WO-2015055755-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF SE (DE) 2015-04-23 — — WO claimed
WO-2015055752-A1 INSECTICIDAL ACTIVE MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF SE (DE) 2015-04-23 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839214-B2 Fungicidal mixture comprising substituted pyridines ME1, DPM1, TH NR1H3 4758/4885NR1H2 4706/4885RXFP1 4041/4885
US-20160227772-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND NAAA, AADAC, PYCARD NR1H3 4768/4885NR1H2 4709/4885RXFP1 2362/4885
US-20160227771-A1 Insecticidal Active Mixtures Comprising Carboxamide Compound ATP5ME, MT-ATP6, ATP5MG NR1H3 3997/4885NR1H2 3440/4885RXFP1 2642/4885
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF MANBA, CMA1, MTX1 NR1H3 3562/4885NR1H2 3519/4885RXFP1 1166/4885
US-20210355139-A1 Pyrimidinium Compounds and Their Mixtures for Combating Animal Pests THOP1, NIT2, DDT NR1H3 2821/4885NR1H2 3042/4885RXFP1 843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.