Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.89 |
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777752 | 0.86 | KLK7 (0.83) | KLK7POLBSMN1; SMN2HTTPKM | |
| SCHEMBL19250385 | 0.85 | KLK7 (0.81) | KLK7POLBSMN1; SMN2HTTPKM | |
| SCHEMBL17660222 | 0.83 | KLK7 (0.78) | KLK7POLBSMN1; SMN2HTTPKM | |
| SCHEMBL12698771 | 0.83 | SMN1; SMN2 (1.00) | KLK7POLBSMN1; SMN2HTTPKM | |
| SCHEMBL18180861 | 0.83 | RAB9A (0.70) | KLK7POLBSMN1; SMN2HTTPKM | |
| SCHEMBL18164418 | 0.83 | HTT (1.00) | KLK7POLBSMN1; SMN2HTTPKM | |
| SCHEMBL15057481 | 0.82 | KLK7 (0.76) | KLK7POLBSMN1; SMN2HTTPKM | |
| SCHEMBL2536044 | 0.81 | LMNA (0.78) | KLK7POLBSMN1; SMN2HTTPKM | |
| SCHEMBL18027751 | 0.80 | ALDH1A1 (0.65) | KLK7POLBSMN1; SMN2HTTPKM | |
| SCHEMBL6828818 | 0.80 | KLK7 (0.58) | KLK7POLBSMN1; SMN2HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9321766-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-20160096832-A1 | KINASE INHIBITORS | ALLERGAN, INC. | 2016-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096832-A1 | KINASE INHIBITORS | ABL1, LCK, ERBB2 | KLK7 2589/4885POLB 1863/4885SMN1; SMN2 4664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.