SCHEMBL1766673

SCHEMBL1766673

Nc1ccc(C(F)(C(F)(F)F)C(F)(F)F)cc1OC(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KIF11 P52732 3/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PDE2A O00408 1/20 0.30
CREBBP Q92793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13516625 0.91
SCHEMBL13516146 0.91
SCHEMBL4184680 0.82 SMN1; SMN2 (0.41) TSHRHSD17B10PDE2A
SCHEMBL5355009 0.81 ALDH1A1 (0.52) RAB9AL3MBTL1ALDH1A1CYP3A4TSHR
SCHEMBL12950731 0.79 PDE4A (0.31) RAB9AL3MBTL1KIF11
SCHEMBL29857386 0.79 PDE4A (0.31) RAB9AL3MBTL1KIF11
SCHEMBL5958645 0.77 MAPT (0.56) RAB9AL3MBTL1ALDH1A1HSD17B10TDP1
SCHEMBL4185017 0.77 MAPT (0.58) RAB9AL3MBTL1ALDH1A1HSD17B10
SCHEMBL31533760 0.76 GAA (0.39) L3MBTL1KIF11ALDH1A1CYP3A4TSHR
SCHEMBL6310104 0.76 GAA (0.39) L3MBTL1KIF11ALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3684181-B1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) 2025-10-22 EP disclosed
US-12377085-B2 Prolonged ectoparasite-controlling agent for animal MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2025-08-05 US disclosed
US-20230226037-A1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2023-07-20 US disclosed
US-11696913-B2 Prolonged ectoparasite-controlling agent for animal MITSUI CHEMICALS AGRO, INC. (JP) 2023-07-11 US disclosed
CN-114591232-A Long-acting control agent for ectoparasites of animals 三井化学AGRO株式会社 2022-06-07 CN disclosed
CN-111132549-B Long-acting control agent for ectoparasites of animals 三井化学AGRO株式会社 2022-04-12 CN disclosed
EP-3205642-B1 ANILINE INTERMEDIATE FOR THE PREPARATION OF AN AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE. MITSUI CHEMICALS AGRO INC (JP) 2022-03-23 EP disclosed
US-20220048847-A1 PROCESS FOR PREPARING SUBSTITUTED ANILINES BAYER AKTIENGESELLSCHAFT (DE) 2022-02-17 US disclosed
EP-3898574-A1 PROCESS FOR PREPARING SUBSTITUTED ANILINES Bayer Aktiengesellschaft (DE) 2021-10-27 EP disclosed
US-20210276958-A1 METHOD FOR PRODUCING SUBSTITUTED N-ARYL PYRAZOLES BAYER AKTIENGESELLSCHAFT (DE) 2021-09-09 US disclosed
US-20110201687-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS AGRO, INC. (JP) 2011-08-18 US disclosed
US-20110201687-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS AGRO, INC. (JP) 2011-08-18 US disclosed
US-20110201687-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS AGRO, INC. (JP) 2011-08-18 US disclosed
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD Mitsui Chemicals Agro., Inc. (JP) 2011-06-09 US disclosed
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD Mitsui Chemicals Agro., Inc. (JP) 2011-06-09 US disclosed
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD Mitsui Chemicals Agro., Inc. (JP) 2011-06-09 US disclosed
EP-2325165-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND PEST CONTROLLING METHOD Mitsui Chemicals Agro, Inc. (JP) 2011-05-25 EP disclosed
EP-2325165-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND PEST CONTROLLING METHOD Mitsui Chemicals Agro, Inc. (JP) 2011-05-25 EP disclosed
EP-2319830-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT Mitsui Chemicals Agro, Inc. (JP) 2011-05-11 EP disclosed
EP-2319830-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT Mitsui Chemicals Agro, Inc. (JP) 2011-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11696913-B2 Prolonged ectoparasite-controlling agent for animal MTX1, ENPP1, CAT RAB9A 1662/4885L3MBTL1 285/4885KIF11 2664/4885
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD L3MBTL1, L3MBTL4, L3MBTL3 RAB9A 1396/4885L3MBTL1 1/4885KIF11 2089/4885
US-20230226037-A1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MTX1, ENPP1, CAT RAB9A 1662/4885L3MBTL1 285/4885KIF11 2664/4885
US-20220048847-A1 PROCESS FOR PREPARING SUBSTITUTED ANILINES CYP1A2, CYP1A1, CYP1B1 RAB9A 1956/4885L3MBTL1 4101/4885KIF11 1069/4885
US-20210276958-A1 METHOD FOR PRODUCING SUBSTITUTED N-ARYL PYRAZOLES CYP4B1, CYP1B1, CYP1A2 RAB9A 1100/4885L3MBTL1 4148/4885KIF11 3026/4885
US-12377085-B2 Prolonged ectoparasite-controlling agent for animal MTX1, ENPP1, CAT RAB9A 1662/4885L3MBTL1 285/4885KIF11 2664/4885
US-20110201687-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE H1-2, H1-4, H1-0 RAB9A 2152/4885L3MBTL1 24/4885KIF11 2478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.