SCHEMBL17667111

SCHEMBL17667111

CC1(C)c2ccccc2-c2ccc(-n3c4c(c5ccccc53)C(C)(C)c3ccc(Br)cc3-4)cc21

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PDE4B Q07343 1/20 0.33
▸ PDK2 Q15119 1/20 0.33
▸ MEN1 O00255 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17667137 0.91 PGR (0.33) PDK2
SCHEMBL17690009 0.86 PGR (0.33) —
SCHEMBL17667126 0.86 PDE4B (0.42) PDE4BMEN1MAPTHTTRAB9A
SCHEMBL17667131 0.85 PDE4B (0.40) PDE4BMEN1MAPTHTTRAB9A
SCHEMBL14822288 0.83 TSPO (0.37) PDK2MEN1MAPTHTTRAB9A
SCHEMBL20262120 0.83 PDK2 (0.35) PDK2
SCHEMBL30025440 0.83 TSPO (0.37) PDK2MEN1MAPTHTTRAB9A
SCHEMBL15871201 0.82 PDK2 (0.34) PDK2
SCHEMBL14928215 0.82 PDK2 (0.34) PDK2
SCHEMBL10307239 0.81 KDM4E (0.40) PDE4BPDK2MEN1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3006426-B1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2019-01-09 — — EP disclosed
US-9985216-B2 Indenoindole derivative and organic electroluminescent element HODOGAYA CHEMICAL CO., LTD. (JP) 2018-05-29 — — US disclosed
US-20160126468-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO., LTD. (JP) 2016-05-05 — — US disclosed
EP-3006426-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2016-04-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160126468-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT IDO2, SLCO2B1, IDO1 PDE4B 4126/4885PDK2 1509/4885MEN1 1686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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