SCHEMBL17667137

SCHEMBL17667137

CC1(C)c2ccccc2-c2ccc(-n3c4c(c5ccccc53)C(C)(C)c3ccccc3-4)cc21

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 7/20 0.33
▸ PDK2 Q15119 3/20 0.31
▸ KDM4E B2RXH2 1/20 0.30
▸ ATM Q13315 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30
▸ IL1R1 P14778 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17690009 0.92 PGR (0.33) PGRKDM4EATML3MBTL1IL1R1
SCHEMBL17667111 0.91 PDE4B (0.33) PDK2
SCHEMBL17734273 0.88 PGR (0.33) PGRKDM4EATML3MBTL1IL1R1
SCHEMBL17677034 0.86 IL1R1 (0.37) PGRKDM4EATML3MBTL1IL1R1
SCHEMBL17689866 0.86 L3MBTL1 (0.42) PGRKDM4EATML3MBTL1IL1R1
SCHEMBL17689954 0.86 L3MBTL1 (0.44) PGRKDM4EATML3MBTL1IL1R1
SCHEMBL13566823 0.86 KDM4E (0.43) PGRPDK2KDM4EATML3MBTL1
SCHEMBL30655846 0.86 KDM4E (0.43) PGRPDK2KDM4EATML3MBTL1
SCHEMBL18803032 0.86 IL1R1 (0.37) PGRPDK2KDM4EATML3MBTL1
SCHEMBL15759584 0.85 ALOX5 (0.42) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3006426-B1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2019-01-09 — — EP disclosed
US-9985216-B2 Indenoindole derivative and organic electroluminescent element HODOGAYA CHEMICAL CO., LTD. (JP) 2018-05-29 — — US disclosed
US-20160126468-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO., LTD. (JP) 2016-05-05 — — US disclosed
EP-3006426-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2016-04-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160126468-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT IDO2, SLCO2B1, IDO1 PGR 916/4885PDK2 1509/4885KDM4E 922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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