Sugi Predict

Sugi Predict / Compounds / SCHEMBL1766958

SCHEMBL1766958

SCHEMBL1766958

CN(C(=O)c1cccc(F)c1)c1cccc(C(=O)Nc2c(I)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2C(F)(F)F)c1F

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KCNJ11 Q14654 2/20 0.35
▸ KCNK3 O14649 2/20 0.33
▸ KCNK9 Q9NPC2 2/20 0.33
▸ CTSS P25774 1/20 0.33
▸ ABCC9 O60706 1/20 0.33
▸ ABCC8 Q09428 1/20 0.33
▸ KCNJ8 Q15842 1/20 0.33
▸ MAPT P10636 2/20 0.33
▸ RXFP1 Q9HBX9 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ HDAC8 Q9BY41 1/20 0.33
▸ POLB P06746 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ DHODH Q02127 1/20 0.32
▸ CLK1 P49759 1/20 0.32
▸ KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29427849 1.00 KCNJ11 (0.35) KCNJ11KCNK3KCNK9CTSSABCC9
SCHEMBL1766315 0.96 KCNJ11 (0.34) KCNJ11KCNK3KCNK9CTSSABCC9
SCHEMBL1766858 0.94 KCNJ11 (0.36) KCNJ11ABCC9ABCC8KCNJ8MAPT
SCHEMBL1766623 0.93 KCNK3 (0.38) KCNK3KCNK9CTSSRXFP1HDAC8
SCHEMBL29427437 0.93 KCNK3 (0.38) KCNK3KCNK9CTSSRXFP1HDAC8
SCHEMBL1766510 0.92 RXFP1 (0.35) CTSSMAPTRXFP1KDM4EHDAC8
SCHEMBL29427441 0.92 RXFP1 (0.35) CTSSMAPTRXFP1KDM4EHDAC8
SCHEMBL22212758 0.91 TSHR (0.37) KCNJ11KCNK3KCNK9ABCC9ABCC8
SCHEMBL20846847 0.91 GPBAR1 (0.35) CTSSRXFP1HDAC8KMT2APTGES
SCHEMBL20846798 0.90 RXFP1 (0.37) KCNK3KCNK9CTSSMAPTRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117396074-A Fungicidal compositions containing oxadiazole compounds PI工业有限公司 2024-01-12 — — CN claimed
US-11839214-B2 Fungicidal mixture comprising substituted pyridines BASF SE (DE) 2023-12-12 — — US claimed
CN-116076518-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-09 — — CN claimed
EP-3978504-A1 CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDINE DERIVATIVES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2022-04-06 — — EP claimed
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF BASF SE (DE) 2022-02-17 — — US claimed
EP-3942933-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF Agrochemical Products B.V. (NL) 2022-01-26 — — EP claimed
CN-108289456-B Mixture of cis-jasmone and bacillus amyloliquefaciens 巴斯夫欧洲公司 2022-01-11 — — CN claimed
EP-3601298-B1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2021-12-01 — — EP claimed
US-20210355139-A1 Pyrimidinium Compounds and Their Mixtures for Combating Animal Pests BASF SE (DE) 2021-11-18 — — US claimed
CN-113367135-A Agricultural mixtures comprising carboxamide compounds 巴斯夫农业化学品有限公司 2021-09-10 — — CN claimed
EP-3057420-A1 USE OF PESTICIDAL ACTIVE CARBOXAMIDE DERIVATIVE IN SOIL AND SEED APPLICATION AND TREATMENT METHODS BASF Agrochemical Products B.V. (NL) 2016-08-24 — — EP claimed
EP-3057419-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF Agrochemical Products B.V. (NL) 2016-08-24 — — EP claimed
EP-3057418-A1 INSECTICIDAL ACTIVE MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF Agrochemical Products, B.V. (NL) 2016-08-24 — — EP claimed
US-20160227772-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2016-08-11 — — US claimed
US-20160227771-A1 Insecticidal Active Mixtures Comprising Carboxamide Compound BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2016-08-11 — — US claimed
WO-2016079043-A1 PESTICIDAL COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND BASF Agro B.V. (NL) 2016-05-26 — — WO claimed
WO-2016059240-A1 METHOD AND PESTICIDAL MIXTURES FOR CONTROLLING PENTATOMIDAE PESTS BASF SE (DE) 2016-04-21 — — WO claimed
WO-2015055757-A1 USE OF PESTICIDAL ACTIVE CARBOXAMIDE DERIVATIVE IN SOIL AND SEED APPLICATION AND TREATMENT METHODS BASF SE (DE) 2015-04-23 — — WO claimed
WO-2015055752-A1 INSECTICIDAL ACTIVE MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF SE (DE) 2015-04-23 — — WO claimed
WO-2015055755-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF SE (DE) 2015-04-23 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839214-B2 Fungicidal mixture comprising substituted pyridines ME1, DPM1, TH KCNJ11 1501/4885KCNK3 1284/4885KCNK9 1874/4885
US-20160227772-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND NAAA, AADAC, PYCARD KCNJ11 3338/4885KCNK3 3874/4885KCNK9 3305/4885
US-20160227771-A1 Insecticidal Active Mixtures Comprising Carboxamide Compound ATP5ME, MT-ATP6, ATP5MG KCNJ11 223/4885KCNK3 386/4885KCNK9 826/4885
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF MANBA, CMA1, MTX1 KCNJ11 4576/4885KCNK3 4049/4885KCNK9 4172/4885
US-20210355139-A1 Pyrimidinium Compounds and Their Mixtures for Combating Animal Pests THOP1, NIT2, DDT KCNJ11 2994/4885KCNK3 2840/4885KCNK9 3849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.