SCHEMBL1767004

SCHEMBL1767004

O=S(=O)(O)c1c[c]c2ccccc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SNCA P37840 1/20 0.40
HSD17B10 Q99714 3/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
CASP6 P55212 4/20 0.36
POLB P06746 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
NSD2 O96028 2/20 0.35
DUSP3 P51452 2/20 0.35
PTPN5 P54829 2/20 0.35
PTPN11 Q06124 2/20 0.35
CASP7 P55210 1/20 0.35
F2 P00734 1/20 0.34
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3952770 0.83 ALDH1A1 (0.43) TSHRSMN1; SMN2SNCAHSD17B10ALDH1A1
SCHEMBL28456393 0.81 ALDH1A1 (0.42) TSHRSMN1; SMN2SNCAHSD17B10ALDH1A1
SCHEMBL16320747 0.81 PTGS2 (0.42) LMNAL3MBTL1
SCHEMBL6632171 0.81 ALDH1A1 (0.46) TSHRSMN1; SMN2SNCAHSD17B10ALDH1A1
SCHEMBL8388156 0.81 LMNA (0.53) LMNA
SCHEMBL28580800 0.80 HTR6 (0.50) TSHRSMN1; SMN2ALDH1A1LMNAPOLB
SCHEMBL1375946 0.79 ALDH1A1 (0.33) TSHRSMN1; SMN2SNCAHSD17B10ALDH1A1
SCHEMBL3823429 0.78 TSHR (0.39) TSHRSMN1; SMN2HSD17B10ALDH1A1LMNA
SCHEMBL17289181 0.77 ALDH1A1 (0.39) SMN1; SMN2ALDH1A1LMNATDP1POLB
SCHEMBL3823585 0.76 SNCA (0.42) TSHRSMN1; SMN2SNCAHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5811081-A Use of hydroxybenzotriazoles for enhancing the sun protection factor of cellulosic fibre materials CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-22 US claimed
EP-0708197-A2 Utilisation of hydroxybenztriazoles for increasing the sun-ray filter index of fibrous cellulosic materials CIBA-GEIGY AG (CH) 1996-04-24 EP claimed
EP-0087113-B1 WATER SOLUBLE DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1986-09-03 EP claimed
EP-2243805-B1 ANTHRAPYRIDONE COMPOUND OR SALT THEREOF, MAGENTA INK COMPOSITION CONTAINING THE ANTHRAPYRIDONE COMPOUND, AND COLORED BODY NIPPON KAYAKU KK (JP) 2014-11-26 EP disclosed
US-7985287-B2 Anthrapyridone compound or a salt thereof, magenta ink composition containing the anthrapyridone compound and colored product NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-26 US disclosed
EP-2317307-A2 Method of analyzing amino- and/or imino-functional compounds, and analytical reagent Ajinomoto Co., Inc. (JP) 2011-05-04 EP disclosed
US-20100291360-A1 Anthrapyridone Compound Or A Salt Thereof, Magenta Ink Composition Containing The Anthrapyridone Compound and Colored Product NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-11-18 US disclosed
EP-2243805-A1 ANTHRAPYRIDONE COMPOUND OR SALT THEREOF, MAGENTA INK COMPOSITION CONTAINING THE ANTHRAPYRIDONE COMPOUND, AND COLORED BODY Nippon Kayaku Kabushiki Kaisha (JP) 2010-10-27 EP disclosed
CN-1616432-A Compound,its use and pharmaceutical compositions comprising same ELAN PHARM INC (US) 2005-05-18 CN disclosed
US-20040231558-A1 Has a clear hue, high light fastness and high moisture resistance MITSUI CHEMICALS, INC. (JP) 2004-11-25 US disclosed
CN-1171878-C Compounds, their use and pharmaceutical compositions containing them ������˹ҩƷ��˾ 2004-10-20 CN disclosed
EP-0719840-A1 Monoazo compounds and method for dyeing or printing fiber materials using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-07-03 EP disclosed
EP-0708197-A2 Utilisation of hydroxybenztriazoles for increasing the sun-ray filter index of fibrous cellulosic materials CIBA-GEIGY AG (CH) 1996-04-24 EP disclosed
EP-0629667-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-21 EP disclosed
EP-0624630-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1994-11-17 EP disclosed
EP-0603595-A1 Fibre reactive dyes, method for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-29 EP disclosed
EP-0548792-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed
EP-0087113-B1 WATER SOLUBLE DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1986-09-03 EP disclosed
EP-0087113-A2 Water soluble disazo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1983-08-31 EP disclosed
US-4040840-A MEROCYANINE DYE HAVING ISOXAZOLE NUCLEUS AND PYRAZOLINE-5-ONE NUCLEUSN FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100291360-A1 Anthrapyridone Compound Or A Salt Thereof, Magenta Ink Composition Containing The Anthrapyridone Compound and Colored Product MLLT3, MLLT1, H1-3 TSHR 3602/4885SMN1; SMN2 1648/4885SNCA 4090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.