SCHEMBL1767320

SCHEMBL1767320

C[C@@H](OC(=O)[C@@H](N)CCC(=O)O)[C@H](N)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.52
GRM8 O00222 1/20 0.52
GRM6 O15303 1/20 0.52
GRIN2D O15399 1/20 0.52
GRIN3B O60391 1/20 0.52
GSR P00390 1/20 0.52
GRIK1 P39086 1/20 0.52
GRM5 P41594 1/20 0.52
GRIA1 P42261 1/20 0.52
GRIA2 P42262 1/20 0.52
GRIA3 P42263 1/20 0.52
SLC1A3 P43003 1/20 0.52
SLC1A2 P43004 1/20 0.52
SLC1A1 P43005 1/20 0.52
GRIA4 P48058 1/20 0.52
GRIN1 Q05586 1/20 0.52
GRIN2A Q12879 1/20 0.52
GRIK2 Q13002 1/20 0.52
GRIK3 Q13003 1/20 0.52
GRIN2B Q13224 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Leucine SCHEMBL6130154 0.91 SLC7A5 (0.51) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL2482058 0.88 ALOX15 (0.53) CYP1A2GRM8GRM6GRIN2DGRIN3B
D-Glutamate SCHEMBL28632361 0.83 SLC1A3 (0.46) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL28554464 0.82 SLC7A5 (0.40) GRIK1GRIA1GRIA2SLC1A3SLC1A2
SCHEMBL4537589 0.82 GABRP (0.54) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL7780572 0.82 GABRP (0.54) CYP1A2GRM8GRM6GRIN2DGRIN3B
Asparagine SCHEMBL6130108 0.82 ALOX15 (0.50) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL3422700 0.81 SLC1A2 (0.45) GRIK1SLC1A3SLC1A2SLC1A1GRIK2
Cysteine SCHEMBL8071966 0.81 ALOX15 (0.49) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL135879 0.80 SLC7A5 (0.41) SLC1A3SLC1A2SLC1A1SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011053167-A1 TRANSCRIPTION FACTOR POLYNUCLEOTIDES AND THEIR USE GRASSLANZ TECHNOLOGY LIMITED (NZ) 2011-05-05 WO claimed
EP-4010364-A1 MODIFIED HUMAN VARIABLE DOMAINS Merus N.V. (NL) 2022-06-15 EP disclosed
WO-2021025555-A1 MODIFIED HUMAN VARIABLE DOMAINS MERUS N.V. (NL) 2021-02-11 WO disclosed
EP-3772518-A1 MODIFIED HUMAN VARIABLE DOMAINS Merus N.V. (NL) 2021-02-10 EP disclosed
US-8900849-B2 Oxygen-regulated microorganisms SCARAB GENOMICS, LLC (US) 2014-12-02 US disclosed
US-20140186957-A1 ENGINEERED TAL EFFECTOR PROTEINS WITH ENHANCED DNA TARGETING CAPACITY FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2014-07-03 US disclosed
US-8354372-B2 Cyclised alpha-conotoxin peptides THE UNIVERSITY OF QUEENSLAND (AU) 2013-01-15 US disclosed
WO-2011053167-A1 TRANSCRIPTION FACTOR POLYNUCLEOTIDES AND THEIR USE GRASSLANZ TECHNOLOGY LIMITED (NZ) 2011-05-05 WO disclosed
US-20090053792-A1 OXYGEN-REGULATED MICROORGANISMS SCARAB GENOMICS, LLC (US) 2009-02-26 US disclosed