Asparagine

Asparagine

SCHEMBL6130108

C[C@@H](OC(=O)[C@@H](N)CCC(N)=O)[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.50
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50
KMT2A Q03164 1/20 0.50
DPP4 P27487 1/20 0.36
DPP8 Q6V1X1 1/20 0.36
DPP9 Q86TI2 1/20 0.36
GRIK1 P39086 10/20 0.36
GRIK2 Q13002 6/20 0.36
SLC1A1 P43005 5/20 0.36
SLC1A3 P43003 5/20 0.36
SLC1A2 P43004 5/20 0.36
GRIA4 P48058 4/20 0.36
GRIK3 Q13003 4/20 0.36
GRIK5 Q16478 4/20 0.36
GRIA2 P42262 3/20 0.36
GRIA1 P42261 2/20 0.36
SLC7A5 Q01650 1/20 0.36
GRM8 O00222 1/20 0.36
GRM6 O15303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2482058 0.93 ALOX15 (0.53) ALOX15BLMPMP22KMT2ADPP4
Asparagine SCHEMBL7763894 0.90 SLC7A5 (0.41) ALOX15BLMPMP22KMT2AGRIK1
Cysteine SCHEMBL8071966 0.87 ALOX15 (0.49) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL1964052 0.86 SLC7A5 (0.39) ALOX15BLMPMP22KMT2AGRIK1
Glutamine SCHEMBL16914546 0.84 KMT2A (0.56) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL1767320 0.82 CYP1A2 (0.52) ALOX15BLMPMP22KMT2ADPP4
Glutamine SCHEMBL829896 0.80 ALOX15 (0.63) ALOX15BLMPMP22KMT2ADPP4
Glutamine SCHEMBL27977814 0.80 ALOX15 (0.63) ALOX15BLMPMP22KMT2ADPP4
Leucine SCHEMBL6130154 0.80 SLC7A5 (0.51) DPP4DPP8DPP9GRIK1GRIK2
Glutamine SCHEMBL6130109 0.79 ALOX15 (0.61) ALOX15BLMPMP22KMT2ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1315752-A4 MODIFIED PROTEINS, ISOLATED NOVEL PEPTIDES, AND USES THEREOF UNIV AUSTRALIAN (AU) 2005-07-06 EP disclosed
US-20040091964-A1 Modified proteins, isolated novel peptides,and uses thereof BOARD PHILLIP (AU) 2004-05-13 US disclosed
EP-1315752-A1 MODIFIED PROTEINS, ISOLATED NOVEL PEPTIDES, AND USES THEREOF THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2003-06-04 EP disclosed
WO-2002018438-A9 MODIFIED PROTEINS, ISOLATED NOVEL PEPTIDES, AND USES THEREOF UNIV AUSTRALIAN (AU) 2002-05-30 WO disclosed
WO-2002018438-A1 MODIFIED PROTEINS, ISOLATED NOVEL PEPTIDES, AND USES THEREOF THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2002-03-07 WO disclosed