Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Asparagine SCHEMBL6130108 | 0.93 | ALOX15 (0.50) | ALOX15BLMPMP22KMT2ADPP4 | |
| Cysteine SCHEMBL8071966 | 0.91 | ALOX15 (0.49) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL1767320 | 0.88 | CYP1A2 (0.52) | ALOX15BLMPMP22KMT2ADPP4 | |
| Glutamine SCHEMBL16914546 | 0.88 | KMT2A (0.56) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL22772958 | 0.83 | ALOX15 (0.57) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL1964052 | 0.83 | SLC7A5 (0.39) | ALOX15BLMPMP22KMT2ASLC1A1 | |
| Glutamine SCHEMBL7696024 | 0.82 | KMT2A (0.49) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL5964545 | 0.80 | ALOX15 (0.52) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL7775146 | 0.80 | ALOX15 (0.52) | ALOX15BLMPMP22KMT2ADPP4 | |
| Leucine SCHEMBL6130154 | 0.80 | SLC7A5 (0.51) | DPP4DPP8DPP9SLC1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544992-A1 | G-PROTEIN-COUPLED RECEPTOR INTERNAL SENSORS | The Regents of The University of California (US) | 2019-10-02 | — | — | EP | claimed |
| WO-2018098262-A1 | G-PROTEIN-COUPLED RECEPTOR INTERNAL SENSORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-31 | — | — | WO | claimed |
| CN-102245208-B | immunoglobulin variants and uses thereof | HOFFMAN-LA ROCHE LTD. (CH) | 2016-03-16 | — | — | CN | claimed |
| CN-117180432-A | Use of inhibitors of oxidized ATM for the treatment of breast cancer | 重庆医科大学 | 2023-12-08 | — | — | CN | disclosed |
| US-20230384333-A1 | GPCR SCREENING METHOD TO IDENTIFY NON-HALLUCINOGENIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-11-30 | — | — | US | disclosed |
| CN-117015712-A | GPCR screening method for identifying non-magic compound | 加利福尼亚大学董事会 | 2023-11-07 | — | — | CN | disclosed |
| US-20230348557-A1 | T cell receptors Targeting Defective DNA Repair Proteins | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2023-11-02 | — | — | US | disclosed |
| EP-4229075-A1 | GPCR SCREENING METHOD TO IDENTIFY NON-HALLUCINOGENIC COMPOUNDS | The Regents of the University of California (US) | 2023-08-23 | — | — | EP | disclosed |
| EP-4099989-A2 | T CELL RECEPTORS TARGETING DEFECTIVE DNA REPAIR PROTEINS | University of Pittsburgh - Of the Commonwealth System of Higher Education (US) | 2022-12-14 | — | — | EP | disclosed |
| WO-2022081631-A1 | GPCR SCREENING METHOD TO IDENTIFY NON-HALLUCINOGENIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2021158962-A2 | T CELL RECEPTORS TARGETING DEFECTIVE DNA REPAIR PROTEINS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-08-12 | — | — | WO | disclosed |
| EP-2377881-A2 | Clostridial toxin activatable clostridial toxins | Allergan, Inc. (US) | 2011-10-19 | — | — | EP | disclosed |
| US-20100239563-A1 | PHARMACEUTICAL COMPOSITION FOR THE PROPHYLAXIS AND/OR TREATMENT OF VIRAL DISEASES | LUDWIG STEPHAN | 2010-09-23 | — | — | US | disclosed |
| US-20090019609-A1 | Expression of Cry3B Insecticidal Protein in Plants | ROMANO CHARLES P | 2009-01-15 | — | — | US | disclosed |
| US-20050129694-A1 | Pharmaceutical composition for the prophylaxis and/or treatment of virus diseases | LUDWIG STEPHAN (DE) | 2005-06-16 | — | — | US | disclosed |
| US-6803203-B1 | PROTEIN KINASES; FOR MONITORING IN VITRO ACTIVITY IN EUKARYOTIC CELLS; DRUG SCREENING; KITS | BROOKHAVEN SCIENCE ASSOCIATES | 2004-10-12 | — | — | US | disclosed |
| US-6803203-B1 | PROTEIN KINASES; FOR MONITORING IN VITRO ACTIVITY IN EUKARYOTIC CELLS; DRUG SCREENING; KITS | BROOKHAVEN SCIENCE ASSOCIATES | 2004-10-12 | — | — | US | disclosed |
| US-20020034570-A1 | Cheese flavoring | SYMRISE GMBH & CO. KG (DE) | 2002-03-21 | — | — | US | disclosed |
| US-6298858-B1 | Tobacco flavoring components of enhanced aromatic content and method of providing same | R. J. REYNOLDS TOBACCO COMPANY | 2001-10-09 | — | — | US | disclosed |
| WO-2000028840-A1 | TOBACCO FLAVORING COMPONENTS OF ENHANCED AROMATIC CONTENT AND METHOD OF PROVIDING SAME | R. J. REYNOLDS TOBACCO COMPANY (US) | 2000-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230384333-A1 | GPCR SCREENING METHOD TO IDENTIFY NON-HALLUCINOGENIC COMPOUNDS | HTR4, HTR6, HTR1A | ALOX15 3974/4885BLM 4150/4885PMP22 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.