SCHEMBL17674263

SCHEMBL17674263

O=C(Oc1ccccc1)c1cc([N+](=O)[O-])ccn1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.58
ALDH1A1 P00352 6/20 0.50
KDM4E B2RXH2 3/20 0.50
GAA P10253 1/20 0.50
F2 P00734 1/20 0.49
PYGL P06737 2/20 0.48
PYGM P11217 2/20 0.48
MAPT P10636 8/20 0.48
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
PPARG P37231 1/20 0.44
HTT P42858 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27668680 0.84 KDM4E (0.54) ALOX5ALDH1A1KDM4EGAAMAPT
SCHEMBL4037805 0.79 ALDH1A1 (0.49) ALDH1A1KDM4EF2PYGLPYGM
SCHEMBL8939375 0.79 MAPT (0.58) ALOX5ALDH1A1KDM4EGAAMAPT
SCHEMBL17674189 0.78 ALDH1A1 (0.58) ALOX5ALDH1A1KDM4EGAAMAPT
SCHEMBL8701481 0.78 KMT2A (0.62) ALDH1A1KDM4EGAAMAPTMEN1
SCHEMBL2481383 0.78 ALDH1A1 (0.53) ALDH1A1KDM4EGAAPYGLPYGM
SCHEMBL69530 0.77 MAPT (0.60) ALOX5ALDH1A1KDM4EMAPTMEN1
SCHEMBL9440318 0.77 ALDH1A1 (0.52) ALDH1A1KDM4EGAAPYGLPYGM
SCHEMBL9440315 0.77 ALDH1A1 (0.52) ALDH1A1KDM4EGAAPYGLPYGM
SCHEMBL17673963 0.77 RXFP1 (0.41) ALDH1A1KDM4EGAAF2PYGL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364300-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-07-30 US claimed
US-20170247478-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2017-08-31 US claimed
EP-3204429-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2017-08-16 EP claimed
WO-2016057388-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-04-14 WO claimed
CN-107567464-B Process for producing polydienes and polydiene copolymers having reduced cold flow properties 株式会社普利司通 2020-04-14 CN disclosed
US-10364300-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-07-30 US disclosed
CN-108602820-A Hetero-1, 5,6, 7-tetrahydro-4H-indol-4-ones 拜耳制药股份公司 2018-09-28 CN disclosed
EP-3204429-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2018-09-05 EP disclosed
US-20170247478-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2017-08-31 US disclosed
EP-3204429-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2017-08-16 EP disclosed
WO-2016057388-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-04-14 WO disclosed