Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21731426 | 0.81 | GAA (0.40) | GAAMAPTKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL21709896 | 0.77 | GAA (0.40) | GAAMAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL17674597 | 0.69 | GAA (0.41) | GAAMAPTKDM4EL3MBTL1CHRNA1 | |
| SCHEMBL16190068 | 0.68 | GAA (0.44) | GAAMAPTKDM4EL3MBTL1CHRNA1 | |
| SCHEMBL7784836 | 0.68 | L3MBTL1 (0.55) | GAAMAPTKDM4EL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10682890 | 0.67 | GAA (0.43) | GAAMAPTKDM4EL3MBTL1CHRNA1 | |
| SCHEMBL7971464 | 0.66 | GAA (0.45) | GAAMAPTKDM4EL3MBTL1CHRNA1 | |
| Ammonia Solution, Strong SCHEMBL16179201 | 0.66 | GAA (0.42) | GAAMAPTKDM4EL3MBTL1CHRNA1 | |
| SCHEMBL137992 | 0.65 | — | — | |
| SCHEMBL21384192 | 0.64 | NFE2L2 (0.45) | GAAMAPTKDM4EL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016055605-A1 | PESTICIDALLY ACTIVE BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-04-14 | — | — | WO | disclosed |
| WO-2016055605-A1 | PESTICIDALLY ACTIVE BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-04-14 | — | — | WO | disclosed |