SCHEMBL7971464

SCHEMBL7971464

Clc1ccc(Cc2cccc(Cl)n2)cn1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.45
MAPT P10636 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
KDM4E B2RXH2 1/20 0.45
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 1/20 0.39
CHRNA1 P02708 1/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNA7 P36544 1/20 0.39
CHRNA4 P43681 1/20 0.39
GRM2 Q14416 1/20 0.38
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17674597 0.85 GAA (0.41) GAAMAPTL3MBTL1KDM4EKMT2A
SCHEMBL21731410 0.85 GAA (0.41) GAAMAPTL3MBTL1KDM4EKMT2A
SCHEMBL21723173 0.85 GAA (0.41) GAAMAPTL3MBTL1KDM4EKMT2A
SCHEMBL21731428 0.82 KDM4E (0.43) GAAMAPTL3MBTL1KDM4EKMT2A
SCHEMBL21731373 0.79 GAA (0.43) GAAMAPTL3MBTL1KDM4EKMT2A
SCHEMBL21682616 0.78 MAPT (0.47) GAAMAPTL3MBTL1KDM4EKMT2A
SCHEMBL7969373 0.77 CYP1A2 (0.44) CHRNB2CHRNA7CHRNA4
SCHEMBL22576217 0.77 ALDH1A1 (0.55) L3MBTL1ALDH1A1
SCHEMBL21731377 0.77 CYP11B1 (0.41) GAAMAPTL3MBTL1KDM4E
SCHEMBL21731372 0.76 GAA (0.40) GAAMAPTL3MBTL1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001017965-A2 CYANOPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO disclosed