Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.52 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18906078 | 0.85 | RAB9A (0.55) | RAB9ANPC1ALDH1A1GLASIRT2 | |
| SCHEMBL997872 | 0.84 | RAB9A (0.59) | RAB9ANPC1SIRT2MEN1KMT2A | |
| SCHEMBL28700456 | 0.83 | TDP1 (0.59) | RAB9ANPC1MEN1KMT2A | |
| SCHEMBL18398718 | 0.83 | LMNA (0.58) | RAB9ANPC1ALDH1A1GLAMEN1 | |
| SCHEMBL29238957 | 0.82 | RAB9A (0.57) | RAB9ANPC1SIRT2MEN1KMT2A | |
| SCHEMBL5011704 | 0.80 | RAB9A (0.86) | RAB9ANPC1DEGS1MEN1KMT2A | |
| SCHEMBL20333591 | 0.80 | TRPV1 (0.54) | RAB9ANPC1ALDH1A1GLASIRT2 | |
| SCHEMBL4899301 | 0.80 | HDAC1 (0.54) | RAB9ANPC1ALDH1A1GLASIRT2 | |
| SCHEMBL17111538 | 0.80 | TRPV1 (0.59) | RAB9ANPC1DEGS1 | |
| SCHEMBL17675304 | 0.80 | L3MBTL1 (0.53) | RAB9ANPC1ALDH1A1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016055982-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS | ACERTA PHARMA B.V. (NL) | 2016-04-14 | — | — | WO | disclosed |