Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17675284 | 0.80 | RAB9A (0.55) | KMT2AMEN1CYP3A4ALDH1A1NPC1 | |
| SCHEMBL15881328 | 0.78 | L3MBTL1 (0.55) | L3MBTL1SORT1KMT2AMEN1GAA | |
| SCHEMBL23015840 | 0.78 | TDP1 (0.56) | L3MBTL1KMT2AMEN1POLBGRM5 | |
| SCHEMBL17675324 | 0.78 | SYK (0.50) | SORT1GAA | |
| SCHEMBL14631434 | 0.77 | CA1 (0.53) | L3MBTL1SORT1KMT2AMEN1GAA | |
| SCHEMBL14298343 | 0.76 | L3MBTL1 (0.54) | L3MBTL1SORT1KMT2AMEN1GAA | |
| SCHEMBL16321370 | 0.76 | ALOX15 (0.51) | L3MBTL1SORT1KMT2AMEN1POLB | |
| SCHEMBL28200980 | 0.74 | LMNA (0.53) | L3MBTL1KMT2AMEN1POLBCYP3A4 | |
| SCHEMBL29141778 | 0.73 | NPC1 (0.55) | L3MBTL1SORT1KMT2AMEN1GAA | |
| SCHEMBL28580981 | 0.73 | MPO (0.50) | L3MBTL1KMT2AMEN1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016055982-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS | ACERTA PHARMA B.V. (NL) | 2016-04-14 | — | — | WO | disclosed |