SCHEMBL17675673

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10473975	0.89	MAPT (0.50)	MAPTPDGFRBFGFR1PDGFRAFLT1
	SCHEMBL5062383	0.88	MAPT (0.52)	MAPTCYP1A2ALDH1A1TDP1LMNA
	SCHEMBL21824100	0.86	ALDH1A1 (0.59)	MAPTCYP1A2ALDH1A1TDP1LMNA
	SCHEMBL13400411	0.86	TSHR (0.49)	MAPTCYP1A2PDGFRBFGFR1PDGFRA
	SCHEMBL27719772	0.86	PDGFRB (0.56)	MAPTCYP1A2PDGFRBFGFR1PDGFRA
	SCHEMBL10653936	0.85	MAPT (0.49)	MAPTCYP1A2ALDH1A1TDP1LMNA
	SCHEMBL492505	0.84	CYP1A2 (0.64)	MAPTCYP1A2ALDH1A1TDP1LMNA
	SCHEMBL1695161	0.84	EGFR (0.48)	MAPTCYP1A2PDGFRBFGFR1PDGFRA
	SCHEMBL5201986	0.84	LMNA (0.49)	MAPTCYP1A2PDGFRBFGFR1PDGFRA
	SCHEMBL7226743	0.83	ALDH1A1 (0.50)	MAPTCYP1A2PDGFRBFGFR1PDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.