Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13827404 | 0.91 | SLC6A9 (0.47) | KMT2ASLC6A9SLC8A1NLRP3MAPT | |
| SCHEMBL13827398 | 0.87 | SLC6A9 (0.42) | POLBKMT2ASLC6A9CYP19A1NLRP3 | |
| SCHEMBL13827229 | 0.86 | SLC6A9 (0.54) | SLC6A9 | |
| SCHEMBL17675751 | 0.85 | SLC6A9 (0.56) | POLBKMT2ASLC6A9LMNA | |
| SCHEMBL17675764 | 0.83 | SLC6A9 (0.42) | KMT2ASLC6A9GHSRMAPTHTR6 | |
| SCHEMBL7895325 | 0.81 | SLC6A9 (0.59) | POLBKMT2ASLC6A9SLC8A1 | |
| SCHEMBL13827333 | 0.81 | ADRB2 (0.38) | SLC6A9GHSRSLC8A1NLRP3 | |
| Hydrochloric Acid SCHEMBL3103386 | 0.81 | SLC6A9 (0.58) | POLBKMT2ASLC6A9SLC8A1 | |
| SCHEMBL17675755 | 0.81 | SLC6A9 (0.50) | KMT2ASLC6A9GHSRMAPTHTR6 | |
| SCHEMBL13738306 | 0.80 | SLC6A9 (0.39) | KMT2ASLC6A9GHSRHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309200-B2 | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-04-12 | — | — | US | disclosed |