Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 4/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17675764 | 0.94 | SLC6A9 (0.42) | SLC6A9ALKBH5GAAKDM4EMAPT | |
| SCHEMBL13827788 | 0.91 | SLC6A9 (0.51) | SLC6A9CYP3A4GAAKDM4EMAPT | |
| SCHEMBL13827328 | 0.90 | SLC6A9 (0.61) | SLC6A9CYP3A4GHSRSLC22A1PRCP | |
| SCHEMBL13738306 | 0.89 | SLC6A9 (0.39) | SLC6A9ALKBH5GAAHTR6OPRM1 | |
| SCHEMBL13827388 | 0.85 | SLC6A9 (0.51) | SLC6A9CYP3A4GAAKDM4EMAPT | |
| SCHEMBL17675761 | 0.85 | SLC6A9 (0.53) | SLC6A9CYP3A4 | |
| SCHEMBL13827790 | 0.84 | SLC6A9 (0.42) | SLC6A9CYP3A4GAAKDM4EMAPT | |
| SCHEMBL13827331 | 0.83 | SLC6A9 (0.52) | SLC6A9KDM4EMAPTSLC22A1PRCP | |
| SCHEMBL13827492 | 0.81 | SLC6A9 (0.49) | SLC6A9CYP3A4GAAKDM4EMAPT | |
| SCHEMBL17675754 | 0.81 | POLB (0.40) | SLC6A9MAPTHTR6GHSRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309200-B2 | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-04-12 | — | — | US | disclosed |